AUF1 Dimer (isoform p37 or p40) [cytosol]

Stable Identifier
R-HSA-450391
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
General

Phosphorylated isoform p40 of AUF1 destabilizes mRNA. Isoform p37 (phosphorylation unknown) also destabilizes mRNA.

Literature References
PubMed ID Title Journal Year
12819195 Regulation of A + U-rich element-directed mRNA turnover involving reversible phosphorylation of AUF1

Wilson, GM, Lu, J, Sutphen, K, Sun, Y, Huynh, Y, Brewer, G

J Biol Chem 2003
12944492 Selective degradation of AU-rich mRNAs promoted by the p37 AUF1 protein isoform

Sarkar, B, Xi, Q, He, C, Schneider, RJ

Mol Cell Biol 2003
Participants
members
Participant Of
input
hasComponent
Inferred To
AUF1 Dimer (isoform p37 or p40) [cytosol] (Bos taurus)
AUF1 Dimer (isoform p37 or p40) [cytosol] (Caenorhabditis elegans)
AUF1 Dimer (isoform p37 or p40) [cytosol] (Canis familiaris)
AUF1 Dimer (isoform p37 or p40) [cytosol] (Danio rerio)
AUF1 Dimer (isoform p37 or p40) [cytosol] (Dictyostelium discoideum)
AUF1 Dimer (isoform p37 or p40) [cytosol] (Drosophila melanogaster)
AUF1 Dimer (isoform p37 or p40) [cytosol] (Gallus gallus)
AUF1 Dimer (isoform p37 or p40) [cytosol] (Mus musculus)
AUF1 Dimer (isoform p37 or p40) [cytosol] (Plasmodium falciparum)
AUF1 Dimer (isoform p37 or p40) [cytosol] (Rattus norvegicus)
AUF1 Dimer (isoform p37 or p40) [cytosol] (Sus scrofa)
AUF1 Dimer (isoform p37 or p40) [cytosol] (Xenopus tropicalis)