p-S271,T275-MAP2K7 [cytosol]

Stable Identifier
R-HSA-450353
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p-S271,T275-MKK7, MAP kinase kinase 7(phosphorylated), MAP2K7
Icon
p-S271,T275-MAP2K7 [cytosol] icon
p-S271,T275-MAP2K7 [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:O14733 MAP2K7
Gene Names
MAP2K7, JNKK2, MEK7, MKK7, PRKMK7, SKK4
Chain
initiator methionine:1, chain:2-419
Reference Genes
BioGPS Gene:5609 MAP2K7
COSMIC (genes):MAP2K7 MAP2K7
CTD Gene:5609 MAP2K7
dbSNP Gene:5609 MAP2K7
ENSEMBL:ENSG00000076984.18 MAP2K7
HGNC:6847 MAP2K7
KEGG Gene (Homo sapiens):5609 MAP2K7
Monarch:5609 MAP2K7
NCBI Gene:5609 MAP2K7
OMIM:603014 MAP2K7
UCSC:O14733 MAP2K7
Reference Transcript
Other Identifiers
11723595_s_at
11723596_a_at
11723597_at
11723598_x_at
11752702_a_at
16857799
209951_PM_s_at
209951_s_at
209952_PM_s_at
209952_s_at
226023_PM_at
226023_at
226053_PM_at
226053_at
3819264
3819265
3819266
3819274
3819275
3819277
3819279
3819281
3819283
3819285
3819286
3819287
3819288
3819289
3819290
3819291
3819292
3819293
3819294
3819295
3819296
3819297
41444_at
5609
59996_at
8025351
A_23_P78628
A_33_P3236651
GE785894
GO:0000165
GO:0000166
GO:0000287
GO:0001934
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0004708
GO:0004713
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006468
GO:0006915
GO:0006970
GO:0007165
GO:0007254
GO:0008022
GO:0008545
GO:0009408
GO:0009411
GO:0009611
GO:0012501
GO:0016301
GO:0016310
GO:0016740
GO:0018108
GO:0019899
GO:0019901
GO:0019903
GO:0023052
GO:0031435
GO:0032200
GO:0032212
GO:0034612
GO:0036211
GO:0038095
GO:0043226
GO:0043507
GO:0043525
GO:0045893
GO:0046330
GO:0046872
GO:0051403
GO:0051973
GO:0070374
GO:0071222
GO:0071347
GO:0071470
GO:0072709
GO:0090398
GO:0098772
GO:0106310
GO:0140096
GO:0140677
GO:1904355
GO:2000671
HMNXSV003016511
HMNXSV003058459
Hs.110299.0.A1_3p_a_at
Hs.296234.0.A1_3p_at
Hs.296234.0.A2_3p_at
ILMN_1781104
PH_hs_0006079
TC19000140.hg
g2811125_3p_a_at
Participates
as an output of
as a member of
Other forms of this molecule
MAP2K7(?-419) [cytosol]
MAP2K7(2-?) [cytosol]
MAP2K7 [cytosol]
Inferred To
phospho-MAP2K7 [cytosol] (Sus scrofa)
phospho-p-S271,T275-MAP2K7 [cytosol] (Canis familiaris)
phospho-p-S271,T275-MAP2K7 [cytosol] (Danio rerio)
phospho-p-S271,T275-MAP2K7 [cytosol] (Dictyostelium discoideum)
phospho-p-S271,T275-MAP2K7 [cytosol] (Mus musculus)
phospho-p-S271,T275-MAP2K7 [cytosol] (Rattus norvegicus)
phospho-p-S271,T275-MAP2K7 [cytosol] (Saccharomyces cerevisiae)
phospho-p-S271,T275-MAP2K7 [cytosol] (Schizosaccharomyces pombe)
Homologues of p-S271,T275-MAP2K7 [cytosol] (Saccharomyces cerevisiae)
Homologues of p-S271,T275-MAP2K7 [cytosol] (Schizosaccharomyces pombe)
Modified Residues
Name
O-phospho-L-serine at 271
Coordinate
271
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 275
Coordinate
275
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
ZINC - Investigational
IntEnz
HPA
GeneCards
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (7)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:O43318 MAP3K7  10 0.674 3
 IntAct:EBI-9998887 (DTP3)-TYR,ARG,PHE      0.672 7
 UniProt:O75293 GA45B      0.645 8
 UniProt:Q9UQF2 JIP1      0.623 5
 UniProt:P08238 HSP90AB1  6 0.564 2
 UniProt:P45983 MAPK8  3 0.483 4
 UniProt:P27986 PIK3R1  16 0.462 3
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