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p-MAPK8,9,10 [nucleoplasm]
Stable Identifier
R-HSA-450253
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Phosphorylated JNKs: MAPK8, MAPK9, MAPK10
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
Oxidative Stress Induced Senescence (Homo sapiens)
Activated JNKs phosphorylate c-JUN (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-17 signaling (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
MAPK targets/ Nuclear events mediated by MAP kinases (Homo sapiens)
Activation of the AP-1 family of transcription factors (Homo sapiens)
Activated JNKs phosphorylate c-JUN (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Phosphorylated MAPKs phosphorylate ATF-2 (Homo sapiens)
Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Innate Immune System (Homo sapiens)
Fc epsilon receptor (FCERI) signaling (Homo sapiens)
FCERI mediated MAPK activation (Homo sapiens)
Activated JNKs phosphorylate c-JUN (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 10 (TLR10) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
MAPK targets/ Nuclear events mediated by MAP kinases (Homo sapiens)
Activation of the AP-1 family of transcription factors (Homo sapiens)
Activated JNKs phosphorylate c-JUN (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Phosphorylated MAPKs phosphorylate ATF-2 (Homo sapiens)
Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Toll Like Receptor 2 (TLR2) Cascade (Homo sapiens)
Toll Like Receptor TLR1:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
MAPK targets/ Nuclear events mediated by MAP kinases (Homo sapiens)
Activation of the AP-1 family of transcription factors (Homo sapiens)
Activated JNKs phosphorylate c-JUN (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Phosphorylated MAPKs phosphorylate ATF-2 (Homo sapiens)
Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Toll Like Receptor TLR6:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
MAPK targets/ Nuclear events mediated by MAP kinases (Homo sapiens)
Activation of the AP-1 family of transcription factors (Homo sapiens)
Activated JNKs phosphorylate c-JUN (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Phosphorylated MAPKs phosphorylate ATF-2 (Homo sapiens)
Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Toll Like Receptor 3 (TLR3) Cascade (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
MAPK targets/ Nuclear events mediated by MAP kinases (Homo sapiens)
Activation of the AP-1 family of transcription factors (Homo sapiens)
Activated JNKs phosphorylate c-JUN (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Phosphorylated MAPKs phosphorylate ATF-2 (Homo sapiens)
Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
MyD88-independent TLR4 cascade (Homo sapiens)
TRIF (TICAM1)-mediated TLR4 signaling (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
MAPK targets/ Nuclear events mediated by MAP kinases (Homo sapiens)
Activation of the AP-1 family of transcription factors (Homo sapiens)
Activated JNKs phosphorylate c-JUN (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Phosphorylated MAPKs phosphorylate ATF-2 (Homo sapiens)
Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
MAPK targets/ Nuclear events mediated by MAP kinases (Homo sapiens)
Activation of the AP-1 family of transcription factors (Homo sapiens)
Activated JNKs phosphorylate c-JUN (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Phosphorylated MAPKs phosphorylate ATF-2 (Homo sapiens)
Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Toll Like Receptor 5 (TLR5) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
MAPK targets/ Nuclear events mediated by MAP kinases (Homo sapiens)
Activation of the AP-1 family of transcription factors (Homo sapiens)
Activated JNKs phosphorylate c-JUN (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Phosphorylated MAPKs phosphorylate ATF-2 (Homo sapiens)
Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
MAPK targets/ Nuclear events mediated by MAP kinases (Homo sapiens)
Activation of the AP-1 family of transcription factors (Homo sapiens)
Activated JNKs phosphorylate c-JUN (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Phosphorylated MAPKs phosphorylate ATF-2 (Homo sapiens)
Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Toll Like Receptor 9 (TLR9) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
MAPK targets/ Nuclear events mediated by MAP kinases (Homo sapiens)
Activation of the AP-1 family of transcription factors (Homo sapiens)
Activated JNKs phosphorylate c-JUN (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Phosphorylated MAPKs phosphorylate ATF-2 (Homo sapiens)
Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Homo sapiens)
p-MAPK8,9,10 [nucleoplasm] (Homo sapiens)
Participants
members
p-T,Y-MAPK8 [nucleoplasm]
(Homo sapiens)
p-T183,Y185-MAPK9 [nucleoplasm]
(Homo sapiens)
p-T221,Y223-MAPK10 [nucleoplasm]
(Homo sapiens)
Participates
as an output of
Activated human JNKs migrate to nucleoplasm (Homo sapiens)
as a member of
Activated MAPK kinases ERK1/2, JNK, p38 [nucleoplasm] (Homo sapiens)
Inferred To
p-MAPK8,9,10 [nucleoplasm]
(Bos taurus)
p-MAPK8,9,10 [nucleoplasm]
(Caenorhabditis elegans)
p-MAPK8,9,10 [nucleoplasm]
(Canis familiaris)
p-MAPK8,9,10 [nucleoplasm]
(Dictyostelium discoideum)
p-MAPK8,9,10 [nucleoplasm]
(Drosophila melanogaster)
p-MAPK8,9,10 [nucleoplasm]
(Gallus gallus)
p-MAPK8,9,10 [nucleoplasm]
(Mus musculus)
p-MAPK8,9,10 [nucleoplasm]
(Rattus norvegicus)
p-MAPK8,9,10 [nucleoplasm]
(Saccharomyces cerevisiae)
p-MAPK8,9,10 [nucleoplasm]
(Schizosaccharomyces pombe)
p-MAPK8,9,10 [nucleoplasm]
(Sus scrofa)
phospho-p-T,Y-MAPK8 [nucleoplasm]
(Danio rerio)
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