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GRIK5 [plasma membrane]
Stable Identifier
R-HSA-450197
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Glutamate receptor, ionotropic kainate 5, GRIK5_HUMAN, KA2
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of kainate receptors upon glutamate binding (Homo sapiens)
Ionotropic activity of kainate receptors (Homo sapiens)
Activation of Ca-permeable Kainate Receptor (Homo sapiens)
Activation of Ca-permeable Kainate receptors (Homo sapiens)
Kainate receptor-glutamate complex [plasma membrane] (Homo sapiens)
Kainate Receptors [plasma membrane] (Homo sapiens)
GRIK5 heteromer with GRIk1/2/3 [plasma membrane] (Homo sapiens)
GRIK5 [plasma membrane] (Homo sapiens)
kainate receptor binds glutamate (Homo sapiens)
Kainate Receptors [plasma membrane] (Homo sapiens)
GRIK5 heteromer with GRIk1/2/3 [plasma membrane] (Homo sapiens)
GRIK5 [plasma membrane] (Homo sapiens)
Kainate receptor-glutamate complex [plasma membrane] (Homo sapiens)
Kainate Receptors [plasma membrane] (Homo sapiens)
GRIK5 heteromer with GRIk1/2/3 [plasma membrane] (Homo sapiens)
GRIK5 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q16478 GRIK5
Gene Names
GRIK5, GRIK2
Chain
signal peptide:1-14, chain:15-980
Reference Genes
BioGPS Gene:2901 GRIK5
COSMIC (genes):GRIK5 GRIK5
CTD Gene:2901 GRIK5
dbSNP Gene:2901 GRIK5
ENSEMBL:ENSG00000105737.10 GRIK5
HGNC:4583 GRIK5
KEGG Gene (Homo sapiens):2901 GRIK5
Monarch:2901 GRIK5
NCBI Gene:2901 GRIK5
OMIM:600283 GRIK5
UCSC:Q16478 GRIK5
Reference Transcript
RefSeq:NM_002088.4 GRIK5
RefSeq:NM_001301030.1 GRIK5
RefSeq:XM_011526863.2 GRIK5
RefSeq:XM_005258821.3 GRIK5
Other Identifiers
0001660450
11755672_a_at
1553168_PM_at
1553168_at
16872682
214966_3p_at
214966_PM_at
214966_at
217509_3p_x_at
217509_PM_x_at
217509_x_at
2901
34904_at
34905_at
34906_g_at
3863381
3863382
3863383
3863384
3863385
3863386
3863387
3863388
3863389
3863390
3863391
3863393
3863394
3863399
3863400
3863401
3863402
3863408
3863410
3863412
3863413
3863414
3863415
3863416
3863418
3863419
3863421
3863422
3863426
3863427
3863428
8037103
A_23_P16063
GE62972
GO:0004970
GO:0005215
GO:0005216
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005886
GO:0006621
GO:0006811
GO:0007215
GO:0007268
GO:0008066
GO:0008328
GO:0012501
GO:0014069
GO:0015276
GO:0015277
GO:0016020
GO:0016021
GO:0016192
GO:0017124
GO:0023052
GO:0030165
GO:0030424
GO:0030425
GO:0031630
GO:0032983
GO:0032991
GO:0034220
GO:0035235
GO:0035249
GO:0038023
GO:0042391
GO:0042734
GO:0042802
GO:0043005
GO:0043025
GO:0043113
GO:0043195
GO:0043204
GO:0043226
GO:0043525
GO:0045202
GO:0045211
GO:0050804
GO:0050877
GO:0051649
GO:0055085
GO:0060079
GO:0060089
GO:0061024
GO:0071333
GO:0098686
GO:0098978
GO:0099055
GO:0099056
GO:0099061
GO:0110165
GO:1904315
HMNXSV003046543
HMNXSV003047154
Hs.128095.0.A1_3p_at
Hs.128095.0.A1_3p_x_at
Hs.249141.0.A1_3p_at
Hs.249141.0.A1_3p_s_at
Hs2.249141.1.S1_3p_at
ILMN_1679595
PH_hs_0040813
TC19001564.hg
Participates
as a component of
GRIK5 heteromer with GRIk1/2/3 [plasma membrane] (Homo sapiens)
Inferred To
glr-4 [plasma membrane]
(Caenorhabditis elegans)
GluRIIA [plasma membrane]
(Drosophila melanogaster)
Homologues of GRIK5 [plasma membrane]
(Caenorhabditis elegans)
Homologues of GRIK5 [plasma membrane]
(Drosophila melanogaster)
Ekar [plasma membrane]
(Drosophila melanogaster)
GluRIIE [plasma membrane]
(Drosophila melanogaster)
Ir21a [plasma membrane]
(Drosophila melanogaster)
Ir75d [plasma membrane]
(Drosophila melanogaster)
GluRIID [plasma membrane]
(Drosophila melanogaster)
Grik5 [plasma membrane]
(Mus musculus)
Grik5 [plasma membrane]
(Rattus norvegicus)
DmelCG11155 [plasma membrane]
(Drosophila melanogaster)
Grik [plasma membrane]
(Drosophila melanogaster)
GluRIIC [plasma membrane]
(Drosophila melanogaster)
glr-6 [plasma membrane]
(Caenorhabditis elegans)
grik5 [plasma membrane]
(Xenopus tropicalis)
glr-5 [plasma membrane]
(Caenorhabditis elegans)
GRIK5 [plasma membrane]
(Bos taurus)
GRIK5 [plasma membrane]
(Caenorhabditis elegans)
GRIK5 [plasma membrane]
(Canis familiaris)
GRIK5 [plasma membrane]
(Danio rerio)
GRIK5 [plasma membrane]
(Drosophila melanogaster)
GRIK5 [plasma membrane]
(Sus scrofa)
clumsy [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_002079.3
,
XP_011525165.1
,
NP_001287959.1
,
XP_005258878.1
ZINC - World Drugs
GRIK5_HUMAN
Guide to Pharmacology - Targets
454
OpenTargets
ENSG00000105737
ZINC - FDA approved
GRIK5_HUMAN
ZINC - Substances
GRIK5_HUMAN
ZINC target
Q16478
ZINC - Biogenic
GRIK5_HUMAN
PRO
Q16478
ZINC - Metabolites
GRIK5_HUMAN
HPA
ENSG00000105737-GRIK5
GeneCards
Q16478
Ensembl
ENST00000301218
,
ENST00000593562
,
ENSG00000105737
,
ENSP00000301218
,
ENSP00000262895
,
ENSP00000470251
,
ENST00000262895
Pharos - Targets
Q16478
ZINC - Predictions - Purchasable
GRIK5_HUMAN
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