Interleukin-3 receptor alpha subunit binds Interleukin-3

Stable Identifier
R-HSA-450074
Type
Reaction [binding]
Species
Homo sapiens
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The Interleukin-3 receptor alpha subunit (IL3Ra) has a single transmembrane domain, a glycosylated extracellular domain and a short (53 amino acids) cytoplasmic tail, containing no tyrosine kinase domain (Kitamura et al. 1991). It binds interleukin-3 with low affinity, and is not capable of signaling by itself.

Literature References
PubMed ID Title Journal Year
1833064 Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors

Kitamura, T, Sato, N, Arai, K, Miyajima, A

Cell 1991
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