Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
IL11RA [plasma membrane]
Stable Identifier
R-HSA-449842
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Interleukin-11 receptor alpha chain, I11RA_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-6 family signaling (Homo sapiens)
IL-6-type cytokine receptor ligand interactions (Homo sapiens)
IL11 binds IL11RA (Homo sapiens)
IL11RA [plasma membrane] (Homo sapiens)
IL11RA:IL11 [plasma membrane] (Homo sapiens)
IL11RA [plasma membrane] (Homo sapiens)
IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Homo sapiens)
IL11RA:IL11 [plasma membrane] (Homo sapiens)
IL11RA [plasma membrane] (Homo sapiens)
IL6RA:IL6:IL6RB:JAKs [plasma membrane] (Homo sapiens)
IL11RA:IL11 [plasma membrane] (Homo sapiens)
IL11RA [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14626 IL11RA
Gene Names
IL11RA
Chain
signal peptide:1-22, chain:23-422, chain:23-
Reference Genes
BioGPS Gene:3590 IL11RA
COSMIC (genes):IL11RA IL11RA
CTD Gene:3590 IL11RA
dbSNP Gene:3590 IL11RA
ENSEMBL:ENSG00000137070 IL11RA
HGNC:5967 IL11RA
KEGG:hsa:3590 IL11RA
Monarch:3590 IL11RA
NCBI Gene:3590 IL11RA
OMIM:600939 IL11RA
UCSC:Q14626 IL11RA
Reference Transcript
RefSeq:NM_001142784.2 IL11RA
Other Identifiers
11721024_a_at
11737464_a_at
11737465_at
1552646_PM_at
1552646_at
17084523
204773_PM_at
204773_at
3167555
3167556
3167557
3167558
3167559
3167560
3167561
3167562
3167563
3167564
3167565
3167566
3167568
3167570
3167571
3167572
3167573
3167574
3167575
3167576
3167577
3167578
3590
496_s_at
8154934
89839_at
89841_g_at
89921_at
A_14_P131240
A_14_P132346
A_14_P200250
A_23_P71867
A_23_P83277
GE59085
GO:0004888
GO:0004896
GO:0004921
GO:0005515
GO:0005576
GO:0005886
GO:0008284
GO:0009897
GO:0016020
GO:0019221
GO:0019970
GO:0032502
GO:0038154
GO:0043235
GO:0048856
GO:0060089
GO:0060322
HMNXSV003021621
Hs2.64310.2.S1_3p_at
ILMN_1653459
ILMN_1664912
ILMN_1720024
PH_hs_0023030
TC09002897.hg
U32324_at
g4758593_3p_at
Participates
as a component of
IL11RA:IL11 [plasma membrane] (Homo sapiens)
as an input of
IL11 binds IL11RA (Homo sapiens)
Inferred To
Il11ra1 [plasma membrane]
(Mus musculus)
Il11ra1 [plasma membrane]
(Rattus norvegicus)
il11ra [plasma membrane]
(Xenopus tropicalis)
IL11RA [plasma membrane]
(Canis familiaris)
IL11RA [plasma membrane]
(Gallus gallus)
IL11RA [plasma membrane]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
1709
ENSEMBL
ENSP00000394391
,
ENST00000602473
,
ENSP00000509204
,
ENSG00000137070
,
ENST00000318041
,
ENST00000690286
,
ENST00000441545
,
ENSP00000326500
,
ENSP00000473647
,
ENSP00000450640
,
ENST00000555981
OpenTargets
ENSG00000137070
GeneCards
IL11RA
HPA
ENSG00000137070-IL11RA
PRO
Q14626
Pharos - Targets
Q14626
GlyGen
Q14626
Orphanet
IL11RA
PDB
8DPU
,
8QY4
,
8DPT
,
6O4P
,
8DPS
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6UX06 OLFM4
3
OLFM4 [specific granule lumen]
(R-HSA-6799634)
OLFM4 [extracellular region]
(R-HSA-6799672)
OLFM4 [tertiary granule lumen]
(R-HSA-6800893)
0.556
3
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text