Reactome | GNPNAT1 [cytosol]

GNPNAT1 [cytosol]

Stable Identifier

R-HSA-449709

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Glucosamine 6-phosphate N-acetyltransferase, GNA1_HUMAN

Locations in the PathwayBrowser

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Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
      - Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
        
        Synthesis of UDP-N-acetyl-glucosamine (Homo sapiens)
        
        Acetylation of glucosamine 6-phosphate to GlcNAc6P (Homo sapiens)
        
        2xGNPNAT1 [cytosol] (Homo sapiens)
        
        GNPNAT1 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q96EK6 GNPNAT1

Gene Names

GNPNAT1, GNA1

Chain

chain:1-184

Reference Genes

BioGPS Gene:64841 GNPNAT1

COSMIC (genes):GNPNAT1 GNPNAT1

CTD Gene:64841 GNPNAT1

dbSNP Gene:64841 GNPNAT1

ENSEMBL:ENSG00000100522 GNPNAT1

HGNC:19980 GNPNAT1

KEGG:hsa:64841 GNPNAT1

Monarch:64841 GNPNAT1

NCBI Gene:64841 GNPNAT1

OMIM:616510 GNPNAT1

UCSC:Q96EK6 GNPNAT1

Reference Transcript

Other Identifiers

11723731_at

11723732_at

11758604_x_at

16793052

225853_PM_at

225853_at

3564871

3564873

3564874

3564875

3564876

3564877

3564878

3564879

3564880

3564881

3564882

3564883

3564884

3564885

3564886

3564887

3564890

3564892

57358_i_at

57359_r_at

61630_at

64841

65257_at

7979196

88477_at

A_23_P429184

A_24_P943040

GE55802

GE88041

GE892191

GO:0000139

GO:0003824

GO:0004343

GO:0005515

GO:0005768

GO:0005794

GO:0005829

GO:0006048

GO:0010008

GO:0016020

GO:0016740

GO:0016746

GO:0016747

GO:0031410

GO:0042802

GO:0043226

GO:0055086

GO:1901135

HMNXSV003029725

Hs.27931.0.S1_3p_at

ILMN_1686235

PH_hs_0026464

TC14001142.hg

Participates

as a component of

2xGNPNAT1 [cytosol] (Homo sapiens)

Inferred To

gna-2 [cytosol] (Caenorhabditis elegans)

gnpnat1 [cytosol] (Danio rerio)

gnpnat1 [cytosol] (Xenopus tropicalis)

GNPNAT1 [cytosol] (Bos taurus)

GNPNAT1 [cytosol] (Canis familiaris)

GNPNAT1 [cytosol] (Dictyostelium discoideum)

GNPNAT1 [cytosol] (Drosophila melanogaster)

GNPNAT1 [cytosol] (Gallus gallus)

GNPNAT1 [cytosol] (Mus musculus)

GNPNAT1 [cytosol] (Saccharomyces cerevisiae)

GNPNAT1 [cytosol] (Schizosaccharomyces pombe)

GNPNAT1 [cytosol] (Sus scrofa)

Ghost homologue of GNPNAT1 [cytosol] (Rattus norvegicus)

Cross References

ENSEMBL

ENST00000216410, ENSP00000496934, ENSP00000216410, ENST00000650397

OpenTargets

ENSG00000100522

HPA

ENSG00000100522-GNPNAT1

PRO

Q96EK6

Pharos - Targets

Q96EK6

GlyGen

Q96EK6

HMDB Protein

HMDBP00052

PDB

3CXS, 2HUZ, 3CXP, 3CXQ, 2O28

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P07148 FABP1	2	FABP1 [nucleoplasm] (R-HSA-1989743) FABP1 [cytosol] (R-HSA-2026981)	0.564	2

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