Reactome | STX3 [plasma membrane]

STX3 [plasma membrane]

Stable Identifier

R-HSA-449131

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Syntaxin-3, STX3_HUMAN

Locations in the PathwayBrowser for interactor UniProt:O95405 ZFYVE9

Expand all

External Reference Information

External Reference

UniProt:Q13277 STX3

Gene Names

STX3, STX3A

Chain

chain:1-289

Reference Genes

BioGPS Gene:6809 STX3

COSMIC (genes):STX3 STX3

CTD Gene:6809 STX3

dbSNP Gene:6809 STX3

ENSEMBL:ENSG00000166900 STX3

HGNC:11438 STX3

KEGG:hsa:6809 STX3

Monarch:6809 STX3

NCBI Gene:6809 STX3

OMIM:600876 STX3

UCSC:Q13277 STX3

Reference Transcript

Other Identifiers

11719533_a_at

11719534_a_at

11747878_a_at

11750017_a_at

16725112

209238_PM_at

209238_at

216985_PM_s_at

216985_s_at

235483_PM_at

235483_at

3332132

3332134

3332135

3332136

3332144

3332145

3332150

3332158

3332159

3332160

3332162

3332163

3332164

3332165

3332166

3332167

3332169

3332170

3332171

3332174

3332175

3332176

3332179

3332183

3332184

3332185

3332186

3332187

3332188

3332190

38381_at

51631_at

6809

71621_r_at

7940191

A_14_P101995

A_14_P119760

A_23_P139143

GE582017

GE59084

GO:0000149

GO:0001750

GO:0001917

GO:0005484

GO:0005515

GO:0005634

GO:0005764

GO:0005773

GO:0005886

GO:0005911

GO:0006836

GO:0006886

GO:0006887

GO:0008021

GO:0008284

GO:0008289

GO:0010468

GO:0012505

GO:0016020

GO:0016192

GO:0016324

GO:0030027

GO:0030141

GO:0030425

GO:0030426

GO:0031175

GO:0031201

GO:0031410

GO:0031629

GO:0042470

GO:0042581

GO:0042582

GO:0042589

GO:0043005

GO:0043226

GO:0045785

GO:0048278

GO:0048787

GO:0050544

GO:0050804

GO:0050921

GO:0060090

GO:0060291

GO:0061024

GO:0061025

GO:0070062

GO:0090174

GO:0098685

GO:0098793

GO:0098794

GO:0098967

GO:0098978

GO:0099003

GO:1903078

GO:2000010

HMNXSV003003068

HMNXSV003054941

Hs.180711.0.S1_3p_at

Hs.82240.0.S3_3p_at

Hs.82240.1.S1_3p_a_at

ILMN_1659544

PH_hs_0004706

PH_hs_0010694

TC11000499.hg

TC11002689.hg

U32315_at

Participates

as a component of

TXLNA:STX3 [plasma membrane] (Homo sapiens)

as an input of

TXLNA (IL14) binds syntaxin3 (Homo sapiens)

Inferred To

Syx1A [plasma membrane] (Drosophila melanogaster)

Stx3 [plasma membrane] (Mus musculus)

Stx3 [plasma membrane] (Rattus norvegicus)

syx-2 [plasma membrane] (Caenorhabditis elegans)

unc-64 [plasma membrane] (Caenorhabditis elegans)

Homologues of STX3 [plasma membrane] (Caenorhabditis elegans)

Homologues of STX3 [plasma membrane] (Dictyostelium discoideum)

syn1B [plasma membrane] (Dictyostelium discoideum)

STX3 [plasma membrane] (Bos taurus)

STX3 [plasma membrane] (Canis familiaris)

STX3 [plasma membrane] (Gallus gallus)

STX3 [plasma membrane] (Sus scrofa)

syn1A [plasma membrane] (Dictyostelium discoideum)

Cross References

RefSeq

NP_001171511.1, XP_005274257.1, NP_004168.1, XP_005274252.1

OpenTargets

ENSG00000166900

ENSEMBL

ENST00000529177, ENSP00000433248, ENSP00000338562, ENST00000337979

HPA

ENSG00000166900-STX3

PRO

Q13277

Pharos - Targets

Q13277

Orphanet

STX3

Interactors (42)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12846 STX4	4	STX4 [plasma membrane] (R-HSA-181519) STX4 [phagocytic vesicle membrane] (R-HSA-2029044) STX4 [cytosol] (R-HSA-114505) p-STX4 [cytosol] (R-HSA-114681)	0.83	8
UniProt:Q9H115 NAPB	1	NAPB [cytosol] (R-HSA-5688553)	0.83	8
UniProt:Q13190 STX5	5	STX5 [cytosol] (R-HSA-9613991) STX5 [Golgi membrane] (R-HSA-6807771) STX5 [ER to Golgi transport vesicle membrane] (R-HSA-5689838) STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688157) STX5 [endoplasmic reticulum membrane] (R-HSA-5689474)	0.666	5
UniProt:O95721 SNAP29	3	SNAP29 [azurophil granule membrane] (R-HSA-6799359) SNAP29 [plasma membrane] (R-HSA-2029020) SNAP29 [Golgi membrane] (R-HSA-6810997)	0.666	4
UniProt:O95405 ZFYVE9			0.571	3
UniProt:O15173 PGRMC2	4	PGRMC2 [nuclear envelope] (R-HSA-9707674) PGRMC2 [nucleoplasm] (R-HSA-9707859) PGRMC2 [endoplasmic reticulum membrane] (R-HSA-9714349) PGRMC2 [endosome membrane] (R-HSA-9715090)	0.556	3
UniProt:Q15800 MSMO1	1	MSMO1 [endoplasmic reticulum membrane] (R-HSA-194648)	0.556	3
UniProt:Q16623 STX1A	5	STX1A [plasma membrane] (R-HSA-449128) STX1A(?-288) [plasma membrane] (R-HSA-5246518) STX1A(1-?) [cytosol] (R-HSA-3065964) STX1A [cytosol] (R-HSA-9609866) STX1A [endoplasmic reticulum membrane] (R-HSA-9609878)	0.556	3
UniProt:Q9H2K0 MTIF3	1	MTIF3 [mitochondrial matrix] (R-HSA-5368284)	0.556	3
UniProt:Q13520 AQP6	1	AQP6 [transport vesicle membrane] (R-HSA-431741)	0.556	3
UniProt:O75208 COQ9	1	COQ9 [mitochondrial inner membrane] (R-HSA-8932994)	0.556	3
UniProt:Q8N5M9 JAGN1			0.556	3
UniProt:Q9GZR5 ELOVL4	1	ELOVL4 [endoplasmic reticulum membrane] (R-HSA-548705)	0.556	3
UniProt:Q6ZT21 TMPPE			0.556	3
UniProt:Q5JX71 F209A			0.556	3
UniProt:Q9H6H4 REEP4			0.556	3
UniProt:Q96TC7 RMD3			0.556	3
UniProt:Q7Z7G2 CPLX4			0.556	3
UniProt:O14880 MGST3	1	MGST3 [endoplasmic reticulum membrane] (R-HSA-176053)	0.556	3
UniProt:Q9NY72 SCN3B	1	SCN3B [plasma membrane] (R-HSA-197921)	0.556	3
UniProt:Q5SR56 MF14B			0.556	3
UniProt:Q8TED1 GPX8	1	GPX8 [endoplasmic reticulum lumen] (R-HSA-3341303)	0.556	3
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.556	3
UniProt:Q9Y282 ERGI3			0.556	3
UniProt:Q9Y320 TMX2			0.556	3
UniProt:Q9NQQ7-3 Q9NQQ73			0.556	3
UniProt:P32856-2 STX2			0.556	3
UniProt:Q9NUH8 TM14B			0.556	3
UniProt:P49447 CY561			0.556	3
UniProt:Q8TDT2 GP152			0.556	3
UniProt:O00559 EBAG9	1	EBAG9 [Golgi membrane] (R-HSA-9018507)	0.556	3
UniProt:Q14802-3 FXYD3			0.556	3
UniProt:Q96MV8 ZDH15			0.556	3
UniProt:P11912 CD79A	2	p-Y188,Y199-CD79A [plasma membrane] (R-HSA-983539) CD79A [plasma membrane] (R-HSA-197154)	0.556	3
UniProt:Q8N4V1 MMGT1	1	MMGT1 [Golgi membrane] (R-HSA-5216137)	0.556	3
UniProt:Q9NQG1 MANBL			0.556	3
UniProt:O00161 SNAP23	5	p-S95-SNAP23 [phagocytic vesicle membrane] (R-HSA-8863923) SNAP23 [phagocytic vesicle membrane] (R-HSA-8863966) SNAP23 [tertiary granule membrane] (R-HSA-6806141) SNAP23 [plasma membrane] (R-HSA-376345) SNAP23 [specific granule membrane] (R-HSA-6806157)	0.547	2
UniProt:P61764 STXBP1	2	STXBP1 [plasma membrane] (R-HSA-2980862) STXBP1 [cytosol] (R-HSA-6794256)	0.527	4
UniProt:Q15833 STXBP2	2	STXBP2 [extracellular region] (R-HSA-8862990) STXBP2 [cytosol] (R-HSA-5617151)	0.527	4
UniProt:O95183 VAMP5			0.527	2
UniProt:P21926 CD9	4	CD9 [plasma membrane] (R-HSA-51717) CD9 [endocytic vesicle membrane] (R-HSA-5334774) CD9 [clathrin-coated endocytic vesicle membrane] (R-HSA-5334779) CD9 [platelet alpha granule membrane] (R-HSA-114585)	0.462	2
ChEBI:16851 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,5-BISPHOSPHATE			0.462	2

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