Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TXLNA [cytosol]
Stable Identifier
R-HSA-449124
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Alpha-taxilin, TXLNA_HUMAN, Interleukin-14
Locations in the PathwayBrowser for interactor UniProt:Q96KQ4 PPP1R13B
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Other interleukin signaling (Homo sapiens)
TXLNA (IL14) binds syntaxin1A (Homo sapiens)
TXLNA [cytosol] (Homo sapiens)
TXLNA (IL14) binds syntaxin3 (Homo sapiens)
TXLNA [cytosol] (Homo sapiens)
TXLNA (IL14) binds syntaxin4 (Homo sapiens)
TXLNA [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P40222 TXLNA
Gene Names
TXLNA, TXLN
Chain
chain:1-546
Reference Genes
BioGPS Gene:200081 TXLNA
COSMIC (genes):TXLNA TXLNA
CTD Gene:200081 TXLNA
dbSNP Gene:200081 TXLNA
ENSEMBL:ENSG00000084652 TXLNA
ENSEMBL_homo_sapiens_GENE:ENSG00000084652.16 TXLNA
HGNC:30685 TXLNA
KEGG Gene (Homo sapiens):200081 TXLNA
Monarch:200081 TXLNA
NCBI Gene:200081 TXLNA
OMIM:608676 TXLNA
UCSC:P40222 TXLNA
Reference Transcript
RefSeq:NM_175852.3 TXLNA
RefSeq:XM_017000562.1 TXLNA
Other Identifiers
11729720_a_at
11750379_x_at
11756485_a_at
16661978
200081
212300_PM_at
212300_at
2328714
2328715
2328716
2328717
2328718
2328719
2328721
2328722
2328723
2328725
2328727
2328729
2328730
2328732
2328733
2328734
2328735
2328736
2328737
2328738
2328739
2328741
2328742
2328743
2328745
2328747
2328749
2328751
38421_at
74720_s_at
7899703
A_23_P51361
A_24_P205627
A_33_P3376007
GE898660
GO:0002376
GO:0005515
GO:0005576
GO:0005737
GO:0005829
GO:0006887
GO:0016020
GO:0016192
GO:0019905
GO:0042113
HMNXSV003045667
Hs.83004.0.S1_3p_at
Hs.83004.0.S1_3p_x_at
ILMN_1737084
PH_hs_0022347
TC01000420.hg
TC01004298.hg
Participates
as a component of
TXLNA:STX1A [plasma membrane] (Homo sapiens)
TXLNA:STX4 [plasma membrane] (Homo sapiens)
TXLNA:STX3 [plasma membrane] (Homo sapiens)
as an input of
TXLNA (IL14) binds syntaxin1A (Homo sapiens)
TXLNA (IL14) binds syntaxin4 (Homo sapiens)
TXLNA (IL14) binds syntaxin3 (Homo sapiens)
Inferred To
Dmel\CG5886 [cytosol]
(Drosophila melanogaster)
Txlna [cytosol]
(Mus musculus)
Txlna [cytosol]
(Rattus norvegicus)
TXLNA [cytosol]
(Bos taurus)
TXLNA [cytosol]
(Caenorhabditis elegans)
TXLNA [cytosol]
(Canis familiaris)
TXLNA [cytosol]
(Dictyostelium discoideum)
TXLNA [cytosol]
(Gallus gallus)
TXLNA [cytosol]
(Sus scrofa)
txlna [cytosol]
(Danio rerio)
Cross References
RefSeq
XP_016856051.1
,
NP_787048.1
OpenTargets
ENSG00000084652
GeneCards
P40222
HPA
ENSG00000084652-TXLNA
Ensembl
ENSP00000362711
,
ENST00000373610
,
ENSP00000362712
,
ENSG00000084652
,
ENST00000373609
PRO
P40222
Pharos - Targets
P40222
HMDB Protein
HMDBP08090
Interactors (109)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8N3L3 TXLNB
0.882
13
UniProt:Q9NPJ6 MED4
1
MED4 [nucleoplasm]
(R-HSA-350263)
0.841
9
UniProt:O76015 KRT38
1
KRT38 [cytosol]
(R-HSA-6809615)
0.801
7
UniProt:O14777 NDC80
1
NDC80 [cytosol]
(R-HSA-375314)
0.8
7
UniProt:Q6A162 KRT40
1
KRT40 [cytosol]
(R-HSA-6809605)
0.782
8
UniProt:P56279 TCL1A
0.782
8
UniProt:Q8N1B4 VPS52
1
VPS52 [trans-Golgi network membrane]
(R-HSA-6811029)
0.782
7
UniProt:Q15323 KRT31
1
KRT31 [cytosol]
(R-HSA-6809616)
0.782
7
UniProt:Q01850 CDR2
0.781
7
UniProt:Q9UBB9 TFIP11
1
TFIP11 [nucleoplasm]
(R-HSA-8869310)
0.781
8
UniProt:Q9H8Y8 GORASP2
2
GORASP2 [Golgi membrane]
(R-HSA-2422385)
p-T222,T225-GORASP2 [Golgi membrane]
(R-HSA-2422965)
0.781
7
UniProt:Q9Y3C0 WASC3
0.781
8
UniProt:Q9UHD2 TBK1
5
pS-172,K48polyUb-TBK1 [cytosol]
(R-HSA-3249397)
p-TBK1 [cytosol]
(R-HSA-9008705)
K63polyUb-K30,K401-TBK1 [cytosol]
(R-HSA-9730430)
TBK1 [cytosol]
(R-HSA-166267)
p-S172-TBK1 [cytosol]
(R-HSA-168379)
0.773
8
UniProt:Q9NYP9 MIS18A
1
MIS18A [nucleoplasm]
(R-HSA-606299)
0.742
5
UniProt:Q13136 PPFIA1
1
PPFIA1 [cytosol]
(R-HSA-383377)
0.742
5
UniProt:Q8TD31-3 CCHCR1
0.718
6
UniProt:Q96K17 BT3L4
0.718
6
UniProt:Q9C0F1 CEP44
0.718
6
UniProt:P37198 NUP62
2
NUP62 [cytosol]
(R-HSA-9634226)
NUP62 [nuclear envelope]
(R-HSA-157713)
0.718
8
UniProt:Q96MF7 NSMCE2
1
NSMCE2 [nucleoplasm]
(R-HSA-2993759)
0.718
6
UniProt:Q6NUQ1 RINT1
1
RINT1 [cytosol]
(R-HSA-6810991)
0.718
6
UniProt:Q9NX55 HYPK
0.718
6
UniProt:Q68CZ6 HAUS3
1
HAUS3 [cytosol]
(R-HSA-8855201)
0.718
9
UniProt:Q05D60 DEUP1
0.718
11
UniProt:P19012 KRT15
1
KRT15 [cytosol]
(R-HSA-6809589)
0.718
6
UniProt:Q15025 TNIP1
1
TNIP1 [cytosol]
(R-HSA-5690853)
0.718
6
UniProt:Q13287 NMI
1
NMI [cytosol]
(R-HSA-9731022)
0.718
9
UniProt:Q63ZY3 KANK2
0.718
6
UniProt:Q8N6Y0 USBP1
0.718
6
UniProt:P35900 KRT20
1
KRT20 [cytosol]
(R-HSA-6809603)
0.718
6
UniProt:O60941 DTNB
0.696
5
UniProt:Q7Z3Y8 KRT27
1
KRT27 [cytosol]
(R-HSA-6809587)
0.666
4
UniProt:Q16623 STX1A
5
STX1A [plasma membrane]
(R-HSA-449128)
STX1A(?-288) [plasma membrane]
(R-HSA-5246518)
STX1A(1-?) [cytosol]
(R-HSA-3065964)
STX1A [cytosol]
(R-HSA-9609866)
STX1A [endoplasmic reticulum membrane]
(R-HSA-9609878)
0.666
4
UniProt:Q93045 STMN2
1
STMN2 [cytosol]
(R-HSA-9696513)
0.666
4
UniProt:O76011 KRT34
1
KRT34 [cytosol]
(R-HSA-6809608)
0.666
4
UniProt:P20290 BTF3
0.666
4
UniProt:Q96MT8 CEP63
1
CEP63 [cytosol]
(R-HSA-380267)
0.659
4
UniProt:Q9NWT6 HIF1AN
1
HIF1AN [cytosol]
(R-HSA-1234154)
0.643
3
UniProt:Q9NUQ3 TXLNG
0.638
4
UniProt:Q96JN2-2 CCDC136
0.631
5
UniProt:O76081 RGS20
1
RGS20 [plasma membrane]
(R-HSA-921136)
0.564
2
UniProt:Q92764 KRT35
1
KRT35 [cytosol]
(R-HSA-6809595)
0.556
3
UniProt:O76013-2 KRT36
0.556
3
UniProt:Q969G3 SMARCE1
1
SMARCE1 [nucleoplasm]
(R-HSA-389258)
0.556
3
UniProt:Q05BL1 Q05BL1
0.556
3
UniProt:Q6PID6 TTC33
0.556
6
UniProt:Q9NPF5 DMAP1
1
DMAP1 [nucleoplasm]
(R-HSA-212166)
0.556
3
UniProt:O60504 SORBS3
1
SORBS3 [cytosol]
(R-HSA-445805)
0.556
3
UniProt:Q9BRV8 SIKE1
1
SIKE1 [cytosol]
(R-HSA-916828)
0.556
3
UniProt:Q8IZU1 FAM9A
0.556
3
UniProt:Q9NRA8 4ET
0.556
3
UniProt:Q86T90 K1328
0.556
3
UniProt:Q5PSV4 BRM1L
0.556
3
UniProt:Q8NA61-2 CBY2
0.556
3
IntAct:EBI-22432104 CCSB ORF ID
0.556
3
UniProt:Q86TI0 TBC1D1
2
TBC1D1 [cytoplasmic vesicle membrane]
(R-HSA-1454718)
p-S237-TBC1D1 [cytosol]
(R-HSA-1454673)
0.556
3
UniProt:Q13516 OLIG2
0.556
3
IntAct:EBI-22312375 CCSB ORF ID
0.556
3
UniProt:Q96H20 SNF8
1
SNF8 [cytosol]
(R-HSA-917711)
0.556
3
UniProt:Q8IYX8 CE57L
0.556
3
UniProt:Q9NS73-5 MBIP
0.556
3
UniProt:P61266 STX1B
3
STX1B(1-?) [cytosol]
(R-HSA-5246520)
STX1B(?-288) [plasma membrane]
(R-HSA-5246519)
STX1B [plasma membrane]
(R-HSA-181479)
0.556
3
UniProt:O95208-2 EPN2
0.556
3
UniProt:O60941-5 DTNB
0.556
3
IntAct:EBI-16435328 CCSB ORF ID
0.556
3
UniProt:O95678 KRT75
1
KRT75 [cytosol]
(R-HSA-6809652)
0.556
3
UniProt:Q9P2K3 RCOR3
0.556
3
UniProt:Q96KQ4 PPP1R13B
1
PPP1R13B [nucleoplasm]
(R-HSA-6799775)
0.556
3
UniProt:P23508 CRCM
0.556
3
UniProt:Q8IYE0 CC146
0.556
3
UniProt:Q9Y250 LZTS1
0.556
3
UniProt:Q8NEF3-2 CCDC112
0.556
3
UniProt:Q8WXA9 SREK1
0.556
3
UniProt:A0A1B0GWI1 A0A1B0GWI1
0.556
5
UniProt:Q2M2I5 KRT24
1
KRT24 [cytosol]
(R-HSA-6809606)
0.556
3
UniProt:Q8NHQ8-2 RASSF8
0.556
3
IntAct:EBI-16439879 CCSB ORF ID
0.556
3
UniProt:Q5TAP6 UTP14C
1
UTP14C [nucleoplasm]
(R-HSA-8867818)
0.556
3
UniProt:Q99459 CDC5L
1
CDC5L [nucleoplasm]
(R-HSA-5420887)
0.556
3
UniProt:Q2TAC2-2 CCDC57
0.556
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:Q6ZUT1 NKAP1
0.556
3
UniProt:Q8IYX8-2 CEP57L1
0.556
3
UniProt:Q86XR8-3 CEP57
0.556
3
UniProt:Q86VQ0 LCA5
0.556
3
UniProt:O75928-2 PIAS2
1
PIAS2-2 [nucleoplasm]
(R-HSA-2993779)
0.556
3
UniProt:Q13625-3 TP53BP2
0.556
3
UniProt:Q9NQY0 BIN3
0.556
3
UniProt:O43395 PRPF3
1
PRPF3 [nucleoplasm]
(R-HSA-6806806)
0.556
3
UniProt:Q8TBF8 FA81A
0.556
3
UniProt:A1A4E9 A1A4E9
0.556
3
UniProt:O95995 GAS8
1
GAS8 [cytosol]
(R-HSA-5633057)
0.556
3
UniProt:Q9NYA3 GOG6A
0.556
3
UniProt:Q8NA61 CBY2
0.556
3
UniProt:P50221 MEOX1
0.556
3
UniProt:P50222 MEOX2
0.556
3
UniProt:Q96M91 CFA53
0.556
3
UniProt:Q9Y2T1 AXIN2
4
AXIN2 [cytosol]
(R-HSA-3640821)
RibC-AXIN2 [cytosol]
(R-HSA-3640842)
Ub-RibC-AXIN2 [cytosol]
(R-HSA-3640859)
ub-AXIN2 [cytosol]
(R-HSA-4641131)
0.556
3
UniProt:Q6ZSJ8 CA122
0.527
3
UniProt:Q96FN4 CPNE2
0.527
3
UniProt:Q96LB3 IFT74
2
IFT74 [cilium]
(R-HSA-5617616)
IFT74 [ciliary tip]
(R-HSA-5625364)
0.527
2
UniProt:Q96HH9 GRM2B
0.527
2
UniProt:Q8N4N8 KIF2B
1
KIF2B [cytosol]
(R-HSA-376259)
0.527
2
UniProt:Q8IUD6 RNF135
1
RNF135 [cytosol]
(R-HSA-936042)
0.527
2
UniProt:Q96DX7 TRI44
0.527
2
UniProt:CYorf15B CY15B
0.499
2
UniProt:Q13765 NACA
0.499
2
UniProt:Q9QYP6 AZI2
0.499
2
UniProt:Q66GS9 CEP135
1
CEP135 [cytosol]
(R-HSA-380266)
0.483
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text