Interleukin-16 is secreted

Stable Identifier
R-HSA-449077
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
extracellular region, cytosol
ReviewStatus
5/5
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Interleukin-16 is secreted
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Interleukin-16 (IL16) does not contain a consensus secretory leader sequence, and the mechanism for its release has not been elucidated. Amino-terminal deletions of IL16 reduce its capacity for secretion (Zhou et al. 1999), but the significance of this is unclear.
Literature References
PubMed ID Title Journal Year
10395686 Processing, secretion, and anti-HIV-1 activity of IL-16 with or without a signal peptide in CD4+ T cells

Devadas, K, Zhou, P, Notkins, AL, Jegorow, A, Tewari, D

J Immunol 1999
Participants
Input
Output
Participates
as an event of
Orthologous Events
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Authored
Jupe, S  (2014-06-04)
Reviewed
Meldal, BH  (2016-01-28)
Created
Jupe, S  (2009-11-27)
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