Reactome | IL32 [cytosol]

IL32 [cytosol]

Stable Identifier

R-HSA-448634

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Interleukin-32, IL32_HUMAN

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RAC3 GTPase cycle (Homo sapiens)
        
        RAC3 binds effectors at the plasma membrane (Homo sapiens)
        
        RAC3 effectors [cytosol] (Homo sapiens)
        
        IL32 [cytosol] (Homo sapiens)
        
        RAC3:GTP:RAC3 effectors [plasma membrane] (Homo sapiens)
        
        RAC3 effectors [cytosol] (Homo sapiens)
        
        IL32 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P24001 IL32

Gene Names

IL32, NK4, TAIF

Chain

signal peptide:1-30, chain:31-234

Reference Genes

BioGPS Gene:9235 IL32

COSMIC (genes):IL32 IL32

CTD Gene:9235 IL32

dbSNP Gene:9235 IL32

ENSEMBL:ENSG00000008517 IL32

HGNC:16830 IL32

KEGG:hsa:9235 IL32

Monarch:9235 IL32

NCBI Gene:9235 IL32

OMIM:606001 IL32

UCSC:P24001 IL32

Reference Transcript

Participates

as a candidate of

RAC3 effectors [cytosol] (Homo sapiens)

as a component of

IL32:PRTN3 [cytosol] (Homo sapiens)

as an input of

Interleukin-32 binds proteinase-3 (Homo sapiens)

Inferred To

IL32 [cytosol] (Bos taurus)

Cross References

OpenTargets

ENSG00000008517

ENSEMBL

ENSP00000448683, ENSP00000411958, ENSP00000432917, ENSP00000433747, ENSP00000432218, ENSP00000447496, ENSP00000437020, ENSP00000008180, ENST00000325568, ENST00000526464, ENST00000396887, ENSP00000446978, ENST00000529550, ENST00000528163, ENST00000534507, ENST00000525643, ENST00000552356, ENSP00000324742, ENSP00000450364, ENST00000549213, ENST00000382213, ENST00000551122, ENSG00000008517, ENSP00000432850, ENST00000548246, ENSP00000449483, ENST00000530538, ENST00000440815, ENST00000533097, ENST00000396890, ENSP00000405063, ENSP00000447812, ENSP00000446624, ENSP00000380096, ENSP00000447979, ENSP00000371648, ENSP00000380099, ENST00000548476, ENST00000008180, ENSP00000431775, ENST00000444393, ENST00000552664, ENST00000531965, ENSP00000436929, ENST00000530890, ENST00000548652, ENSP00000433177

GeneCards

IL32

HPA

ENSG00000008517-IL32

PRO

P24001

Pharos - Targets

P24001

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6NTF9-3 Q6NTF93			0.556	3

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