Reactome | IL32 [cytosol]

IL32 [cytosol]

Stable Identifier

R-HSA-448634

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Interleukin-32, IL32_HUMAN

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RAC3 GTPase cycle (Homo sapiens)
        
        RAC3 binds effectors at the plasma membrane (Homo sapiens)
        
        RAC3 effectors [cytosol] (Homo sapiens)
        
        IL32 [cytosol] (Homo sapiens)
        
        RAC3:GTP:RAC3 effectors [plasma membrane] (Homo sapiens)
        
        RAC3 effectors [cytosol] (Homo sapiens)
        
        IL32 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P24001 IL32

Gene Names

IL32, NK4, TAIF

Chain

signal peptide:1-30, chain:31-234

Reference Genes

BioGPS Gene:9235 IL32

COSMIC (genes):IL32 IL32

CTD Gene:9235 IL32

dbSNP Gene:9235 IL32

ENSEMBL:ENSG00000008517.19 IL32

HGNC:16830 IL32

KEGG Gene (Homo sapiens):9235 IL32

Monarch:9235 IL32

NCBI Gene:9235 IL32

OMIM:606001 IL32

UCSC:P24001 IL32

Reference Transcript

Other Identifiers

0001400670

11734890_a_at

11735174_a_at

11736394_x_at

11753515_a_at

16815355

203828_PM_s_at

203828_s_at

3645627

3645628

3645629

3645630

3645631

3645632

3645633

3645634

3645635

3645636

3645639

3645641

3645642

3645643

3645644

3645645

3645646

3645647

3645648

39119_s_at

7992828

9235

A_14_P108391

A_23_P15146

A_33_P3346826

GE61110

GO:0002376

GO:0005125

GO:0005515

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005829

GO:0006952

GO:0006955

GO:0007155

GO:0007165

GO:0016020

GO:0023052

GO:0098772

HMNXSV003028665

ILMN_1778010

ILMN_2368530

M59807_at

PH_hs_0000122

TC16000099.hg

g4758811_3p_a_at

Participates

as a candidate of

RAC3 effectors [cytosol] (Homo sapiens)

as a component of

IL32:PRTN3 [cytosol] (Homo sapiens)

as an input of

Interleukin-32 binds proteinase-3 (Homo sapiens)

Cross References

RefSeq

NP_001012651.1, NP_001012653.1, NP_001012650.1, NP_001012652.1, NP_001012654.1, NP_001295007.1, NP_001012736.1, NP_004212.4, NP_001012649.1

OpenTargets

ENSG00000008517

GeneCards

P24001

HPA

ENSG00000008517-IL32

Ensembl

ENST00000534507, ENSP00000450364, ENSP00000380099, ENST00000531965, ENSP00000431775, ENSP00000436929, ENST00000549213, ENST00000548246, ENSP00000432850, ENSP00000449483, ENSP00000433177, ENSP00000324742, ENST00000525643, ENST00000548476, ENSP00000448683, ENST00000533097, ENST00000440815, ENST00000548652, ENSP00000405063, ENSP00000447496, ENST00000530538, ENST00000444393, ENSP00000411958, ENST00000325568, ENSP00000008180, ENST00000396887, ENSG00000008517, ENSP00000371648, ENST00000528163, ENST00000529550, ENST00000526464, ENST00000396890, ENST00000008180, ENST00000382213, ENSP00000432917, ENST00000552356, ENSP00000433747, ENSP00000432218, ENST00000551122, ENSP00000437020, ENST00000530890, ENSP00000380096, ENSP00000446624, ENSP00000446978, ENST00000552664, ENSP00000447979, ENSP00000447812

PRO

P24001

Pharos - Targets

P24001

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6NTF9-3 Q6NTF93			0.556	3