The Interleukin-33 (IL33):Interleukin-1 receptor-like 1 (IL1RL1, ST2) complex binds the membrane-associated form of Interleukin-1 receptor accessory protein (IL1RAP-1). After IL33:IL1RL1 ligand binding, IL1RL1 undergoes a conformational change, which allows the recruitment of IL1RAP-1 (Lingel et al. 2009, Liu et al. 2013).
Fairbrother, WJ, Niebuhr, M, Wiesmann, C, Pan, B, Appleton, BA, Lingel, A, Weiss, TM, Bazan, JF
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