Reactome | IFNL1 [extracellular region]

IFNL1 [extracellular region]

Stable Identifier

R-HSA-448598

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

IL29, Interleukin-29, IL29_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8IU54 IFNL1

Gene Names

IFNL1, IL29, ZCYTO21

Chain

signal peptide:1-19, chain:20-200

Reference Genes

BioGPS Gene:282618 IFNL1

COSMIC (genes):IFNL1 IFNL1

CTD Gene:282618 IFNL1

dbSNP Gene:282618 IFNL1

ENSEMBL:ENSG00000182393 IFNL1

HGNC:18363 IFNL1

KEGG:hsa:282618 IFNL1

Monarch:282618 IFNL1

NCBI Gene:282618 IFNL1

OMIM:607403 IFNL1

UCSC:Q8IU54 IFNL1

Reference Transcript

RefSeq:NM_172140.1 IFNL1

Other Identifiers

11735904_at

1552917_PM_at

1552917_at

16861961

282618

3832908

3832909

3832910

3832912

3832913

3832914

3832915

8028613

A_23_P337800

GE556221

GO:0002376

GO:0002829

GO:0005102

GO:0005125

GO:0005576

GO:0005615

GO:0006355

GO:0007259

GO:0008285

GO:0032002

GO:0032003

GO:0032696

GO:0032714

GO:0032729

GO:0038196

GO:0042531

GO:0043381

GO:0045087

GO:0045345

GO:0045581

GO:0045892

GO:0045893

GO:0046427

GO:0048018

GO:0050778

GO:0051607

GO:0098542

GO:0098586

GO:0098772

HMNXSV003004165

Hs2.406744.1.S1_3p_s_at

Hs2.406745.1.S1_3p_at

ILMN_1684570

ILMN_2149624

PH_hs_0019318

TC19000540.hg

Participates

as a component of

as an input of

IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Homo sapiens)

Inferred To

ifnl3 [extracellular region] (Xenopus tropicalis)

IFNL1 [extracellular region] (Bos taurus)

Ghost homologue of IFNL1 [extracellular region] (Mus musculus)

Ghost homologue of IFNL1 [extracellular region] (Rattus norvegicus)

ifnl3.4 [extracellular region] (Xenopus tropicalis)

Homologues of IFNL1 [extracellular region] (Xenopus tropicalis)

LOC101734074 [extracellular region] (Xenopus tropicalis)

IFNL3 [extracellular region] (Gallus gallus)

IL29L [extracellular region] (Canis familiaris)

IL29 [extracellular region] (Sus scrofa)

Cross References

RefSeq

NP_742152.1

ENSEMBL

ENSP00000517467, ENSP00000329991, ENST00000709027, ENST00000333625

OpenTargets

ENSG00000182393

HPA

ENSG00000182393-IFNL1

PRO

Q8IU54

Pharos - Targets

Q8IU54

GlyGen

Q8IU54

PDB

3OG4, 3OG6

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8IZJ0 IFNL2	1	IFNL2 [extracellular region] (R-HSA-448587)	0.527	2