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IL17RA [plasma membrane]
Stable Identifier
R-HSA-447176
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Interleukin-17 receptor A, IL17R, I17RA_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
IL17RA and IL17RC bind IL17A dimer,IL17F dimer,IL17A:IL17F (Homo sapiens)
8:IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA:IL17RC:IL17A dimer,L17F dimer,IL17A:IL17F [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
SARS-CoV-2 8 binds IL17RA (Homo sapiens)
8:IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-17 signaling (Homo sapiens)
IL17RA and IL17RB bind IL25 dimer (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL25 dimer:IL17RA:IL17RB [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA and IL17RC bind IL17A dimer,IL17F dimer,IL17A:IL17F (Homo sapiens)
8:IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA:IL17RC:IL17A dimer,L17F dimer,IL17A:IL17F [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA:IL17RE binds IL17C dimer (Homo sapiens)
IL17C dimer:IL17RA:IL17RE [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96F46 IL17RA
Gene Names
IL17RA, IL17R
Chain
signal peptide:1-32, chain:33-866
Reference Genes
BioGPS Gene:23765 IL17RA
COSMIC (genes):IL17RA IL17RA
CTD Gene:23765 IL17RA
dbSNP Gene:23765 IL17RA
ENSEMBL:ENSG00000177663.15 IL17RA
HGNC:5985 IL17RA
KEGG Gene (Homo sapiens):23765 IL17RA
Monarch:23765 IL17RA
NCBI Gene:23765 IL17RA
OMIM:605461 IL17RA
UCSC:Q96F46 IL17RA
Reference Transcript
RefSeq:NM_001289905.1 IL17RA
RefSeq:NM_014339.6 IL17RA
Other Identifiers
11740065_at
16926813
205707_PM_at
205707_at
228685_PM_at
228685_at
229101_PM_at
229101_at
229295_PM_at
229295_at
23765
36229_at
3936044
3936045
3936052
3936055
3936057
3936059
3936062
3936063
3936065
3936066
3936067
3936068
3936069
3936070
3936071
3936072
3936073
3936074
3936076
3936077
3936078
3936080
3936082
3936084
51614_at
53215_at
77161_at
8071069
A_14_P120600
A_23_P17706
A_32_P103815
A_33_P3224809
A_33_P3540143
GE59260
GO:0002250
GO:0002376
GO:0005102
GO:0005515
GO:0005576
GO:0005886
GO:0006954
GO:0007166
GO:0009615
GO:0016020
GO:0023052
GO:0030163
GO:0030368
GO:0032736
GO:0032747
GO:0032754
GO:0032755
GO:0045087
GO:0048870
GO:0050729
GO:0050832
GO:0060089
GO:0071621
GO:0072537
GO:0072538
GO:0097400
GO:0098542
GO:0110165
GO:1900017
GO:2000340
HMNXSV003037847
Hs.146912.0.A1_3p_at
Hs.146912.0.A1_3p_x_at
Hs.177376.0.A1_3p_at
Hs.48353.0.A1_3p_at
ILMN_1728724
PH_hs_0003390
PH_hs_0007599
TC22000019.hg
TC22000936.hg
TC22000937.hg
g7657229_3p_at
Participates
as a component of
IL17C dimer:IL17RA:IL17RE [plasma membrane] (Homo sapiens)
IL25 dimer:IL17RA:IL17RB [plasma membrane] (Homo sapiens)
IL17RA:IL17RC:IL17A dimer,L17F dimer,IL17A:IL17F [plasma membrane] (Homo sapiens)
8:IL17RA [plasma membrane] (Homo sapiens)
as an input of
IL17RA:IL17RE binds IL17C dimer (Homo sapiens)
IL17RA and IL17RB bind IL25 dimer (Homo sapiens)
IL17RA and IL17RC bind IL17A dimer,IL17F dimer,IL17A:IL17F (Homo sapiens)
SARS-CoV-2 8 binds IL17RA (Homo sapiens)
Cross References
RefSeq
NP_055154.3
,
NP_001276834.1
Guide to Pharmacology - Targets
1738
OpenTargets
ENSG00000177663
GeneCards
Q96F46
HPA
ENSG00000177663-IL17RA
Ensembl
ENST00000319363
,
ENST00000612619
,
ENSP00000479970
,
ENSP00000320936
,
ENSG00000177663
PRO
Q96F46
Pharos - Targets
Q96F46
Orphanet
20144
PDB
3JVF
,
7ZAN
,
5NAN
,
7UWM
,
5N9B
,
4NUX
,
4HSA
,
7UWN
,
7UWL
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DTC8 8
2
8 [extracellular region]
(R-COV-9755410)
8 [endoplasmic reticulum lumen]
(R-COV-9727283)
0.623
3
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