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IL17RA [plasma membrane]
Stable Identifier
R-HSA-447176
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Interleukin-17 receptor A, IL17R, I17RA_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
IL17RA and IL17RC bind IL17A dimer,IL17F dimer,IL17A:IL17F (Homo sapiens)
8:IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA:IL17RC:IL17A dimer,L17F dimer,IL17A:IL17F [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
SARS-CoV-2 8 binds IL17RA (Homo sapiens)
8:IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-17 signaling (Homo sapiens)
IL17RA and IL17RB bind IL25 dimer (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL25 dimer:IL17RA:IL17RB [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA and IL17RC bind IL17A dimer,IL17F dimer,IL17A:IL17F (Homo sapiens)
8:IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA:IL17RC:IL17A dimer,L17F dimer,IL17A:IL17F [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA:IL17RE binds IL17C dimer (Homo sapiens)
IL17C dimer:IL17RA:IL17RE [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
IL17RA [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96F46 IL17RA
Gene Names
IL17RA, IL17R
Chain
signal peptide:1-32, chain:33-866
Reference Genes
BioGPS Gene:23765 IL17RA
COSMIC (genes):IL17RA IL17RA
CTD Gene:23765 IL17RA
dbSNP Gene:23765 IL17RA
ENSEMBL:ENSG00000177663 IL17RA
HGNC:5985 IL17RA
KEGG:hsa:23765 IL17RA
Monarch:23765 IL17RA
NCBI Gene:23765 IL17RA
OMIM:605461 IL17RA
UCSC:Q96F46 IL17RA
Reference Transcript
RefSeq:NM_001289905.1 IL17RA
RefSeq:NM_014339.6 IL17RA
Other Identifiers
11740065_at
16926813
205707_PM_at
205707_at
228685_PM_at
228685_at
229101_PM_at
229101_at
229295_PM_at
229295_at
23765
36229_at
3936044
3936045
3936052
3936053
3936054
3936055
3936056
3936057
3936058
3936059
3936060
3936061
3936062
3936063
3936064
3936065
3936066
3936067
3936068
3936069
3936070
3936071
3936072
3936073
3936074
3936076
3936077
3936078
3936080
3936082
3936084
51614_at
53215_at
77161_at
8071069
A_14_P120600
A_23_P17706
A_32_P103815
A_33_P3224809
A_33_P3540143
GE59260
GO:0002250
GO:0002376
GO:0005102
GO:0005515
GO:0005576
GO:0005886
GO:0006954
GO:0007166
GO:0009615
GO:0016020
GO:0030163
GO:0030368
GO:0032736
GO:0032747
GO:0032754
GO:0032755
GO:0038173
GO:0045087
GO:0048870
GO:0050729
GO:0050832
GO:0060089
GO:0071621
GO:0072537
GO:0072538
GO:0097400
GO:0098542
GO:1900017
GO:2000340
HMNXSV003037847
Hs.146912.0.A1_3p_at
Hs.146912.0.A1_3p_x_at
Hs.177376.0.A1_3p_at
Hs.48353.0.A1_3p_at
ILMN_1728724
PH_hs_0003390
PH_hs_0007599
TC22000019.hg
TC22000936.hg
TC22000937.hg
g7657229_3p_at
Participates
as a component of
IL17C dimer:IL17RA:IL17RE [plasma membrane] (Homo sapiens)
IL25 dimer:IL17RA:IL17RB [plasma membrane] (Homo sapiens)
IL17RA:IL17RC:IL17A dimer,L17F dimer,IL17A:IL17F [plasma membrane] (Homo sapiens)
8:IL17RA [plasma membrane] (Homo sapiens)
as an input of
IL17RA:IL17RE binds IL17C dimer (Homo sapiens)
IL17RA and IL17RB bind IL25 dimer (Homo sapiens)
IL17RA and IL17RC bind IL17A dimer,IL17F dimer,IL17A:IL17F (Homo sapiens)
SARS-CoV-2 8 binds IL17RA (Homo sapiens)
Cross References
RefSeq
NP_001276834.1
,
NP_055154.3
Guide to Pharmacology - Targets
1738
ENSEMBL
ENST00000612619
,
ENSP00000479970
,
ENST00000319363
,
ENSP00000320936
OpenTargets
ENSG00000177663
HPA
ENSG00000177663-IL17RA
PRO
Q96F46
Pharos - Targets
Q96F46
GlyGen
Q96F46
Orphanet
IL17RA
PDB
5N9B
,
7UWL
,
7UWM
,
4HSA
,
7ZAN
,
4NUX
,
3JVF
,
5NAN
,
7UWN
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DTC8 8
2
8 [extracellular region]
(R-COV-9755410)
8 [endoplasmic reticulum lumen]
(R-COV-9727283)
0.623
3
UniProt:Q709F0 ACAD11
1
ACAD11 [mitochondrial inner membrane]
(R-HSA-5695987)
0.527
2
UniProt:Q8WZ79 DNS2B
0.527
3
UniProt:Q16552 IL17A
1
IL17A [extracellular region]
(R-HSA-447093)
0.527
2
UniProt:Q9Y2Y8 PRG3
3
PRG3 [tertiary granule lumen]
(R-HSA-6800905)
PRG3 [extracellular region]
(R-HSA-6806299)
PRG3 [specific granule lumen]
(R-HSA-6799555)
0.527
2
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