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IL5 [extracellular region]
Stable Identifier
R-HSA-447159
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Interleukin-5, IL5_HUMAN
Locations in the PathwayBrowser for interactor UniProt:P32927 CSF2RB
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Homo sapiens)
Interleukin-5 is a homodimer (Homo sapiens)
IL5 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P05113 IL5
Gene Names
IL5
Chain
signal peptide:1-19, chain:20-134
Reference Genes
BioGPS Gene:3567 IL5
COSMIC (genes):IL5 IL5
CTD Gene:3567 IL5
dbSNP Gene:3567 IL5
ENSEMBL:ENSG00000113525 IL5
ENSEMBL_homo_sapiens_GENE:ENSG00000113525.10 IL5
HGNC:6016 IL5
KEGG Gene (Homo sapiens):3567 IL5
Monarch:3567 IL5
NCBI Gene:3567 IL5
OMIM:147850 IL5
UCSC:P05113 IL5
Reference Transcript
RefSeq:NM_000879.2 IL5
RefSeq:XM_011543373.2 IL5
RefSeq:XM_011543374.2 IL5
Other Identifiers
11738281_a_at
16999799
207952_PM_at
207952_at
2875385
2875386
2875387
2875388
2875389
2875390
3567
436_at
8114023
A_24_P209047
GE59662
GO:0002376
GO:0002639
GO:0005125
GO:0005137
GO:0005515
GO:0005576
GO:0005615
GO:0006351
GO:0006355
GO:0006954
GO:0006955
GO:0008083
GO:0008284
GO:0019221
GO:0023052
GO:0030154
GO:0030890
GO:0036211
GO:0038043
GO:0045645
GO:0045893
GO:0046427
GO:0048018
GO:0048856
GO:0050731
GO:0065003
GO:0071803
GO:0098772
HMNXSV003014274
ILMN_1709300
ILMN_2207190
PH_hs_0000300
TC05001769.hg
TC05003236.hg
X04688_at
g4504670_3p_at
Participates
as an input of
Interleukin-5 is a homodimer (Homo sapiens)
as a component of
IL5 homodimer [extracellular region] (Homo sapiens)
Inferred To
Il5 [extracellular region]
(Mus musculus)
Il5 [extracellular region]
(Rattus norvegicus)
IL5 [extracellular region]
(Bos taurus)
IL5 [extracellular region]
(Canis familiaris)
IL5 [extracellular region]
(Gallus gallus)
IL5 [extracellular region]
(Sus scrofa)
Cross References
RefSeq
XP_011541676.1
,
NP_000870.1
,
XP_011541675.1
OpenTargets
ENSG00000113525
HPA
ENSG00000113525-IL5
GeneCards
P05113
ZINC target
P05113
Ensembl
ENSG00000113525
,
ENSP00000231454
,
ENST00000231454
PRO
P05113
Pharos - Targets
P05113
ZINC - Predictions - Purchasable
IL5_HUMAN
HMDB Protein
HMDBP02456
PDB
3VA2
,
1HUL
,
3QT2
,
8TLD
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q01344-2 IL5RA
0.618
4
UniProt:Q01344 IL5RA
1
IL5RA [plasma membrane]
(R-HSA-450072)
0.524
2
UniProt:P32927 CSF2RB
6
CSF2RB S271L [plasma membrane]
(R-HSA-5688879)
p-Y593,Y628-CSF2RB [plasma membrane]
(R-HSA-912312)
CSF2RB [plasma membrane]
(R-HSA-879960)
p-S585-CSF2RB [plasma membrane]
(R-HSA-914170)
p-Y593-CSF2RB [plasma membrane]
(R-HSA-914092)
CSF2RB R211Efs*54 [plasma membrane]
(R-HSA-5688863)
0.524
2
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