IRAK4 is activated by autophosphorylation

Stable Identifier
R-HSA-446634
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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IRAK4 is activated by autophosphorylation at 3 positions within the kinase activation loop, Thr-342, Thr-345 and Ser-346.

Literature References
PubMed ID Title Journal Year
17141195 Regulation of IRAK-4 kinase activity via autophosphorylation within its activation loop

Cheng, H, Addona, T, Keshishian, H, Dahlstrand, E, Lu, C, Dorsch, M, Li, Z, Wang, A, Ocain, TD, Li, P, Parsons, TF, Jaffee, B, Xu, Y

Biochem Biophys Res Commun 2007
Participants
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Orthologous Events
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Created