Association of PARVA with TESK1

Stable Identifier
R-HSA-446372
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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The association of PARVA with TESK1 appears to suppress cell spreading (Lalonde et al. 2005). TESK1 can phosphorylate cofilin and promote F-actin polymerization and cell spreading (Tsumura et al., 2005 ; Toshima et al., 2001; Leeksma et al., 2002). PARVA associates with testicular protein kinase 1 (TESK1) and inhibits its activity (Lalonde et al. 2005).
Literature References
PubMed ID Title Journal Year
15817463 Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin

Bouverat, BP, Brown, MC, Turner, CE, LaLonde, DP

J Biol Chem 2005
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Orthologous Events
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