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Localization of the PINCH-ILK-PARVIN complex to focal adhesions
Stable Identifier
R-HSA-446343
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Cell-Cell communication (Homo sapiens)
Cell junction organization (Homo sapiens)
Cell-extracellular matrix interactions (Homo sapiens)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions (Homo sapiens)
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The interactions among ILK, PINCH, and parvins are necessary but not sufficient for localization of ILK to cell-ECM adhesions (Zhang et al., 2002). Additional proteins that interact with PINCH-ILK-parvin complex components likely participate in mediating its localization (reviewed in Wu, 2004).
Literature References
PubMed ID
Title
Journal
Year
15246679
The PINCH-ILK-parvin complexes: assembly, functions and regulation
Wu, C
Biochim Biophys Acta
2004
Participants
Events
ILK interacts with beta-1 integrin
(Homo sapiens)
PARVA associates with Paxillin
(Homo sapiens)
Participates
as an event of
Cell-extracellular matrix interactions (Homo sapiens)
Orthologous Events
Localization of the PINCH-ILK-PARVIN complex to focal adhesions (Bos taurus)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions (Caenorhabditis elegans)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions (Canis familiaris)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions (Danio rerio)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions (Drosophila melanogaster)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions (Gallus gallus)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions (Mus musculus)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions (Rattus norvegicus)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions (Sus scrofa)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions (Xenopus tropicalis)
Authored
Matthews, L (2009-10-12)
Reviewed
Wu, C (2009-11-12)
Created
Matthews, L (2009-11-12)
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