Reactome | VASP [cytosol]

VASP [cytosol]

Stable Identifier

R-HSA-446323

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

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Locations in the PathwayBrowser for interactor UniProt:Q15942 ZYX

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External Reference Information

External Reference

UniProt:P50552 VASP

Gene Names

VASP

Chain

initiator methionine:, chain:2-380

Reference Genes

BioGPS Gene:7408 VASP

COSMIC (genes):VASP VASP

CTD Gene:7408 VASP

dbSNP Gene:7408 VASP

ENSEMBL:ENSG00000125753 VASP

HGNC:12652 VASP

KEGG:hsa:7408 VASP

Monarch:7408 VASP

NCBI Gene:7408 VASP

OMIM:601703 VASP

UCSC:P50552 VASP

Reference Transcript

RefSeq:NM_003370.3 VASP

Other Identifiers

11744034_a_at

16863307

202205_PM_at

202205_at

3836318

3836319

3836320

3836325

3836326

3836327

3836328

3836329

3836330

3836332

3836333

3836334

3836335

3836336

3836337

3836338

3836339

3836340

3836341

3836342

3836343

3836344

3836345

3836346

3836347

3836348

3836349

3836350

3836351

3836359

39105_at

7408

8029710

A_14_P129018

A_23_P119102

GE60407

GO:0001843

GO:0003779

GO:0005515

GO:0005522

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0005923

GO:0005925

GO:0007010

GO:0007411

GO:0008092

GO:0008154

GO:0015629

GO:0017124

GO:0030027

GO:0030036

GO:0030175

GO:0030838

GO:0031258

GO:0031527

GO:0042995

GO:0043226

GO:0045296

GO:0051289

GO:0065003

GO:0070062

GO:0098794

GO:0098978

HMNXSV003057504

ILMN_1743646

ILMN_1812001

PH_hs_0033125

TC19000649.hg

X98534_s_at

g4507868_3p_x_at

Participates

as a member of

as a component of

MIGFILIN:VASP [cytosol] (Homo sapiens)

as an input of

Migfilin interacts with VASP (Homo sapiens)

Inferred To

VASP [cytosol] (Canis familiaris)

VASP [cytosol] (Gallus gallus)

VASP [cytosol] (Sus scrofa)

vaspa [cytosol] (Danio rerio)

vasp [cytosol] (Dictyostelium discoideum)

vasp [cytosol] (Xenopus tropicalis)

ena [cytosol] (Drosophila melanogaster)

unc-34 [cytosol] (Caenorhabditis elegans)

Vasp [cytosol] (Mus musculus)

Vasp [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_003361.1

OpenTargets

ENSG00000125753

ENSEMBL

ENST00000245932, ENSP00000245932

HPA

ENSG00000125753-VASP

PRO

P50552

Pharos - Targets

P50552

GlyGen

P50552

HMDB Protein

HMDBP02824

PDB

8GAU, 3CHW, 2PBD, 8GAT, 2PAV, 1EGX, 1USE, 1USD

Interactors (30)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15942 ZYX			0.742	5
UniProt:Q9P2A4 ABI3			0.718	9
UniProt:Q9NYB9 ABI2	2	p-4S-ABI2 [cytosol] (R-HSA-2029003) ABI2 [cytosol] (R-HSA-1671647)	0.666	5
UniProt:Q9C026 TRIM9	1	TRIM9 [cytosol] (R-HSA-976054)	0.666	4
UniProt:O95684 CEP43	3	FGFR1OP(2-163)-FGFR1(429-822) fusion [cytosol] (R-HSA-1604533) FGFR1OP(2-163)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1838994) FGFR1OP [cytosol] (R-HSA-380309)	0.666	5
UniProt:Q702N8 XIRP1			0.654	5
UniProt:Q9UQB8-4 BAIAP2			0.645	6
UniProt:Q9UIG4 PS1C2			0.601	4
UniProt:Q9RI12 YPKA			0.581	4
UniProt:P07737 PFN1	2	PFN1 [cytosol] (R-HSA-203081) PFN1 [extracellular region] (R-HSA-350755)	0.564	2
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.564	2
UniProt:Q8IZP0-5 ABI1			0.556	3
UniProt:Q13296 SG2A2			0.556	3
UniProt:Q15418 RPS6KA1	7	p-S221,T359,S363,S380,T573,S732-RPS6KA1 [nucleoplasm] (R-HSA-444292) p-T359,S363,S380.T573,S732-RPS6KA1 [cytosol] (R-HSA-9619993) p-S221,T459,S363,S380,T573,S732-RPS6KA1 [cytosol] (R-HSA-9619871) p-T359,S363,T573-RPS6KA1 [cytosol] (R-HSA-9619957) RPS6KA1 [cytosol] (R-HSA-444256) p-4S,T359,T573-RPS6KA1 [nucleoplasm] (R-HSA-199829) RPS6KA1 [nucleoplasm] (R-HSA-199860)	0.544	4
UniProt:Q9Y6A5 TACC3	1	TACC3 [cytosol] (R-HSA-2160956)	0.527	2
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:Q9UI08 EVL	1	EVL [cytosol] (R-HSA-426403)	0.527	3
UniProt:Q7Z7A3 CTU1	1	CTU1 [cytosol] (R-HSA-6782266)	0.527	3
UniProt:Q15771 RAB30	3	RAB30 [Golgi membrane] (R-HSA-8849598) GGC-RAB30 [cytosol] (R-HSA-8873972) RAB30 [cytosol] (R-HSA-8873677)	0.527	2
UniProt:Q969X6 UTP4	1	CIRH1A [nucleoplasm] (R-HSA-6790662)	0.527	2
UniProt:O00178 GTPB1			0.527	3
UniProt:Q15561 TEAD4	1	TEAD4 [nucleoplasm] (R-HSA-2032780)	0.527	2
UniProt:P22736 NR4A1	2	p-S351-NR4A1 [nucleoplasm] (R-HSA-199846) NR4A1 [nucleoplasm] (R-HSA-199831)	0.524	2
UniProt:A6NGG8 PCARE			0.508	2
UniProt:Q92636 NSMAF	1	NSMAF [cytosol] (R-HSA-5626992)	0.499	2
UniProt:P79114 MYO10			0.489	2
UniProt:O43559 FRS3	3	p-5Y-FRS3 [plasma membrane] (R-HSA-191475) FRS3 [plasma membrane] (R-HSA-191482) p-Y-FRS3 [plasma membrane] (R-HSA-9032427)	0.488	2
UniProt:Q96MA1 DMRTB			0.488	2
UniProt:P21673 SAT1	1	SAT1 [cytosol] (R-HSA-351236)	0.488	2
UniProt:P63261 ACTG1	3	ACTG1 [plasma membrane] (R-HSA-196044) ACTG1 [lysosomal membrane] (R-HSA-196169) ACTG1 [cytosol] (R-HSA-201858)	0.483	2

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