Dolichyl-phosphate-glucose is flipped toward the luminal side of the ER membrane (Imbach T et al, 1999). The exact mechanism and proteins involved in this step are not clear yet, but it is known that it must be carried out by a different flippase than the one that catalyzes the flipping of the N-glycan precursor (Sanyal S et al, 2008).
Imbach, T, Burda, P, Kuhnert, P, Wevers, RA, Aebi, M, Berger, EG, Hennet, T
Sanyal, S, Frank, CG, Menon, AK
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