Cytosolic UAP1 catalyzes the reaction of N-acetyl-D-glucosamine 1-phosphate (GlcNAc1P) and UTP to UDP-N-acetyl-D-glucosamine and pyrophosphate. Structural studies indicate that the active form of the enzyme is a dimer (Peneff C et al, 2001).
Fassy, F, Monnier, C, Peneff, C, Harnois, M, Ferrari, P, Bourne, Y, Charrier, V, Zamboni, V, Winter, J, Taburet, Y
UDP-N-acetylglucosamine diphosphorylase activity of 2xUAP1 [cytosol]
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