Reactome | ESRRG [nucleoplasm]

ESRRG [nucleoplasm]

Stable Identifier

R-HSA-446166

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Estrogen-related receptor gamma, ERR3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P62508 ESRRG

Gene Names

ESRRG, ERR3, ERRG2, KIAA0832, NR3B3

Chain

chain:1-458

Reference Genes

BioGPS Gene:2104 ESRRG

COSMIC (genes):ESRRG ESRRG

CTD Gene:2104 ESRRG

dbSNP Gene:2104 ESRRG

ENSEMBL:ENSG00000196482 ESRRG

HGNC:3474 ESRRG

KEGG Gene (Homo sapiens):2104 ESRRG

Monarch:2104 ESRRG

NCBI Gene:2104 ESRRG

OMIM:602969 ESRRG

UCSC:P62508 ESRRG

Reference Transcript

Other Identifiers

0000580021

0006760242

11729079_s_at

11729080_a_at

11737691_a_at

11741090_a_at

11741647_a_at

11749456_a_at

11756583_a_at

207981_s_at

209966_x_at

2104

2455934

2455935

2455936

2455937

2455944

2455950

2455951

2455952

2455970

2455975

2455976

2455977

2455978

2455979

2455980

2455983

2455993

2456013

2456014

2456016

2456017

2456018

2456035

2456064

2456107

2456176

2456182

31843_at

7924309

A_23_P74900

A_24_P7965

GE54543

GO:0000228

GO:0000790

GO:0000977

GO:0000981

GO:0001228

GO:0003674

GO:0003677

GO:0003700

GO:0003707

GO:0004879

GO:0005496

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0006355

GO:0006367

GO:0007165

GO:0008134

GO:0008150

GO:0008270

GO:0008289

GO:0009058

GO:0034641

GO:0042025

GO:0042592

GO:0043167

GO:0043226

GO:0043401

GO:0043565

GO:0045893

GO:0045944

GO:0046872

GO:0048384

GO:0050682

GO:0070491

GO:0120162

GO:1990837

ILMN_1661994

ILMN_1717593

ILMN_1804064

PH_hs_0009100

TC01006110.hg

g4092074_3p_a_at

g4503604_3p_a_at

Participant Of

hasMember

NR [nucleoplasm]

Inferred To

Esrrg [nucleoplasm] (Mus musculus)

Esrrg [nucleoplasm] (Rattus norvegicus)

esrrga [nucleoplasm] (Danio rerio)

ERR [nucleoplasm] (Drosophila melanogaster)

ESRRG [nucleoplasm] (Bos taurus)

ESRRG [nucleoplasm] (Canis familiaris)

ESRRG [nucleoplasm] (Gallus gallus)

ESRRG [nucleoplasm] (Sus scrofa)

ftsj3 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

XP_011507582.1, XP_011507576.1, XP_011507581.1, NP_001230439.1, NP_001230444.1, XP_016856138.1, XP_016856120.1, XP_011507577.1, NP_001230448.1, NP_001230438.1, XP_016856121.1, XP_011507580.1, XP_016856130.1, NP_001429.2, XP_016856122.1, NP_001230447.1, XP_011507571.1, XP_016856131.1, NP_996317.1, XP_016856123.1, XP_016856132.1, NP_001230441.1, XP_016856124.1, XP_016856133.1, XP_016856125.1, XP_016856134.1, NP_001230440.1, XP_016856126.1, XP_011507570.1, XP_016856135.1, NP_001230434.1, XP_016856127.1, NP_996318.1, XP_016856128.1, NP_001230443.1, XP_011507578.1, XP_011507569.1, XP_016856136.1, NP_001230442.1, XP_016856129.1, NP_001230436.1, XP_011507579.1, NP_001127757.1, XP_016856137.1, NP_001230435.1

ZINC - World Drugs

ERR3_HUMAN

OpenTargets

ENSG00000196482

ZINC - Substances

ERR3_HUMAN

ZINC - Biogenic

ERR3_HUMAN

ZINC target

P62508

PRO

P62508

PDB

2P7G, 2ZBS, 6I63, 2GPV, 1KV6, 6I62, 2GP7, 6A6K, 1VJB, 6I61, 2EWP, 2E2R, 5YSO, 2GPP, 1TFC, 2GPU, 2P7A, 2P7Z, 6K3N, 6I67, 6I66, 2ZAS, 2GPO, 6I65, 6I64, 2ZKC

ZINC - Metabolites

ERR3_HUMAN

HPA

ENSG00000196482-ESRRG

GeneCards

P62508

Ensembl

ENST00000361395, ENSP00000386171, ENSP00000481528, ENSP00000355907, ENST00000487276, ENST00000366940, ENST00000391890, ENSP00000354584, ENSP00000375761, ENSP00000419594, ENSP00000419155, ENST00000463665, ENST00000359162, ENST00000616180, ENSP00000417374, ENST00000361525, ENST00000366937, ENST00000366938, ENST00000493748, ENST00000493603, ENST00000360012, ENSG00000196482, ENSP00000355904, ENSP00000355905, ENSP00000353108, ENSP00000355225, ENSP00000418629, ENSP00000352077, ENST00000408911

ZINC - Predictions - Purchasable

ERR3_HUMAN

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UBK2 PPARGC1A	4	p-T263,S266,T299-PPARGC1A [nucleoplasm] (R-HSA-1592224) SUMO1-K184-PPARGC1A [nucleoplasm] (R-HSA-3903023) p-T178,S539-PPARGC1A [nucleoplasm] (R-HSA-1592204) PPARGC1A [nucleoplasm] (R-HSA-442481)	0.722	4
UniProt:A0MZ66 SHTN1	1	KIAA1598 [cytosol] (R-HSA-443599)	0.556	3

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