Reactome | IL1B,Myr82K-Myr83K-IL1A:IL1R1

IL1B,Myr82K-Myr83K-IL1A:IL1R1

Stable Identifier

R-HSA-445753

Type

Reaction [binding]

Species

Homo sapiens

Compartment

extracellular region, plasma membrane

Synonyms

Interleukin-1 receptor type 1 binds Interleukin 1

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Interleukin-1 receptor type 1 (IL1R1) is the receptor responsible for transmitting the inflammatory effects of Interleukin-1 (IL1).

Literature References

PubMed ID	Title	Journal	Year
8327496	Interleukin 1 signaling occurs exclusively via the type I receptor Sims, JE, Gayle, MA, Slack, JL, Alderson, MR, Bird, TA, Giri, JG, Colotta, F, Re, F, Mantovani, A, Shanebeck, K	Proc Natl Acad Sci U S A	1993
2946959	The cell surface receptors for interleukin-1 alpha and interleukin-1 beta are identical Dower, SK, Kronheim, SR, Hopp, TP, Cantrell, M, Deeley, M, Gillis, S, Henney, CS, Urdal, DL	Nature	1986