Aquaporin-3 passively transports water out of cell

Stable Identifier
Reaction [transition]
Homo sapiens
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Aquaporin-3 (AQP3) passively transports water and glycerol across the plasma membrane according to the osmotic gradient. AQP3 is expressed in airway epithelia, secretory glands, skin, the collecting ducts of the kidney, and the basolateral surface of intestinal epithelium..
Literature References
PubMed ID Title Journal Year
9374640 Aquaporins in complex tissues. II. Subcellular distribution in respiratory and glandular tissues of rat

Christensen, BM, Nielsen, S, Agre, P, King, LS

Am J Physiol 1997
18678926 Compartmentalization of aquaporins in the human intestine

Isokpehi, R, Rajnarayanan, RV, Cohly, HH

Int J Environ Res Public Health 2008
7503232 Aquaporin-3 water channel localization and regulation in rat kidney

Marples, D, Echevarria, M, Ecelbarger, CA, Terris, J, Knepper, MA, Frindt, G, Nielsen, S

Am J Physiol 1995
7526388 Cloning and expression of AQP3, a water channel from the medullary collecting duct of rat kidney

Echevarria, M, Tate, SS, Frindt, G, Windhager, EE

Proc Natl Acad Sci U S A 1994
9374639 Aquaporins in complex tissues. I. Developmental patterns in respiratory and glandular tissues of rat

Nielsen, S, Agre, P, King, LS

Am J Physiol 1997
7538665 Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes

Turck, CW, Verkman, AS, Frigeri, A, Gropper, MA

Proc Natl Acad Sci U S A 1995
8063828 Cloning of a water channel homolog expressed in brain meningeal cells and kidney collecting duct that functions as a stilbene-sensitive glycerol transporter

Ma, T, Verkman, AS, Frigeri, A, Hasegawa, H

J Biol Chem 1994
9369468 Mercury-sensitive residues and pore site in AQP3 water channel

Marumo, F, Gu, Y, Kuwahara, M, Ishibashi, K, Sasaki, S

Biochemistry 1997
15703994 Distribution of AQP2 and AQP3 water channels in human tissue microarrays

Marples, D, Wray, S, Mobasheri, A

J Mol Histol 2005
Catalyst Activity

water channel activity of AQP3 tetramer [plasma membrane]

Orthologous Events
Cross References
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