Reactome | Release Of ADP From Myosin

Release Of ADP From Myosin

Stable Identifier

R-HSA-445705

Type

Reaction [dissociation]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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As soon as the actin and myosin filaments become competent for contraction, the swiveling head of myosin pulls itself along the actin filament. This movement changes the shape of the pocket to which ADP is bound, freeing the ADP molecule.

Literature References

PubMed ID	Title	Journal	Year
2526655	Characterization and differential expression of human vascular smooth muscle myosin light chain 2 isoform in nonmuscle cells Kumar, CC, Mohan, SR, Zavodny, PJ, Narula, SK, Leibowitz, PJ	Biochemistry	1989
3780718	Isoforms of myosin and actin in human, monkey and rat myometrium. Comparison of pregnant and non-pregnant uterus proteins Cavaillé, F, Janmot, C, Ropert, S, d'Albis, A	Eur J Biochem	1986