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CHOL-N-palmitoyl-L-cysteine-IHH(28-202)
Stable Identifier
R-HSA-445149
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Indian hedgehog protein N product, IHH, IHH_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class B/2 (Secretin family receptors) (Homo sapiens)
Patched binds Smoothened (Homo sapiens)
Patched:Hedgehog [plasma membrane] (Homo sapiens)
Hh-Np [extracellular region] (Homo sapiens)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog ligand biogenesis (Homo sapiens)
Release of Hh-Np from the secreting cell (Homo sapiens)
Hh-Np binds SCUBE2 in the extracellular region to promote long-range signalling (Homo sapiens)
Hh-Np:SCUBE2 [extracellular region] (Homo sapiens)
Hh-Np [extracellular region] (Homo sapiens)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (Homo sapiens)
NOTUM releases Hh-Np:GPC5 from the plasma membrane (Homo sapiens)
Hh-Np:GPC5 [extracellular region] (Homo sapiens)
Hh-Np [extracellular region] (Homo sapiens)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14623 IHH
Gene Names
IHH
Chain
signal peptide:1-27, chain:28-411, chain:28-202, chain:203-411
Reference Genes
BioGPS Gene:3549 IHH
COSMIC (genes):IHH IHH
CTD Gene:3549 IHH
dbSNP Gene:3549 IHH
ENSEMBL:ENSG00000163501 IHH
HGNC:5956 IHH
KEGG Gene (Homo sapiens):hsa:3549 IHH
Monarch:3549 IHH
NCBI Gene:3549 IHH
OMIM:600726 IHH
UCSC:Q14623 IHH
Reference Transcript
RefSeq:NM_002181.3 IHH
Other Identifiers
0005720121
11725278_at
11725279_at
16908552
215420_at
229358_at
34618_at
3549
3K7G
3K7H
3K7I
3K7J
3N1F
3N1M
3N1O
3N1P
8059067
89808_at
899_at
A_33_P3338698
AAA62178
AAH34757
AAI36588
AAI36589
AB018076
BAA33523
BC034757
BC136587
BC136588
CCDS33380
CH471063
EAW70675
ENSG00000163501
ENSP00000295731
ENST00000295731
EntrezGene:3549
GE508441
GO:0000003
GO:0000902
GO:0001501
GO:0001503
GO:0001569
GO:0001649
GO:0001701
GO:0001708
GO:0001763
GO:0001944
GO:0001947
GO:0002053
GO:0002376
GO:0003382
GO:0003406
GO:0003413
GO:0003674
GO:0005113
GO:0005509
GO:0005575
GO:0005576
GO:0005578
GO:0005615
GO:0005623
GO:0005886
GO:0006029
GO:0006508
GO:0007155
GO:0007165
GO:0007224
GO:0007267
GO:0007275
GO:0007389
GO:0008150
GO:0008219
GO:0008233
GO:0008283
GO:0008284
GO:0009058
GO:0009790
GO:0009880
GO:0016020
GO:0016539
GO:0016787
GO:0021700
GO:0022607
GO:0030154
GO:0030198
GO:0030704
GO:0031016
GO:0032355
GO:0032967
GO:0033085
GO:0033088
GO:0033089
GO:0034641
GO:0035264
GO:0035988
GO:0040007
GO:0040008
GO:0042592
GO:0042733
GO:0043010
GO:0043066
GO:0043167
GO:0043473
GO:0045453
GO:0045596
GO:0045880
GO:0045944
GO:0046638
GO:0046639
GO:0046872
GO:0048074
GO:0048469
GO:0048557
GO:0048596
GO:0048646
GO:0048666
GO:0048745
GO:0048856
GO:0050679
GO:0051216
GO:0051604
GO:0060135
GO:0060220
GO:0060323
GO:0061053
GO:0072498
GO:0090136
HGNC:5956
Hs.115274.0.A1_3p_at
Hs.654504
Hs.69351.0.S1_3p_at
IHH
IHH-201
ILMN_1801953
IPR000320
IPR001657
IPR001767
IPR003586
IPR003587
IPR006141
IPR009045
IPR028992
IPR033385
L38517
L38517_at
MIM:112500
MIM:600726
MIM:607778
NM_002181
NP_002172
PF01079
PF01085
PH_hs_0038474
PR00632
SM00305
SM00306
TC02002786.hg
uc002vjo.3
UPI0000035883
Participant Of
hasCandidate
Hh-Np [extracellular region]
Other forms of this molecule
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [plasma membrane]
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen]
ub-N4glycoAsn-IHH(203-411) [endoplasmic reticulum lumen]
ub-N4glycoAsn-IHH(203-411) [cytosol]
2xHC-IHH(28-411) [endoplasmic reticulum lumen]
N4glycoAsn-IHH(203-411) [endoplasmic reticulum lumen]
CHOL-IHH(28-202) [endoplasmic reticulum lumen]
N4glycoAsn-2xHC-IHH(28-411) [endoplasmic reticulum lumen]
IHH [extracellular region]
Inferred To
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (Bos taurus)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (Danio rerio)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (Drosophila melanogaster)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (Gallus gallus)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (Mus musculus)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (Rattus norvegicus)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (Sus scrofa)
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (Taeniopygia guttata)
Homologues of CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region] (Danio rerio)
Modified Residues
Name
N-palmitoyl-L-cysteine at 28
Coordinate
28
PsiMod Name
N-palmitoyl-L-cysteine [MOD:00069]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to N-palmitoyl-L-cysteine.
Name
glycine cholesterol ester at 202
Coordinate
202
PsiMod Name
glycine cholesterol ester [MOD:00314]
PsiMod Definition
A protein modification that effectively converts a glycine residue to glycine cholesterol ester.
Cross References
RefSeq
NP_002172.2
GeneCards
Q14623
DOCK Blaster
3K7G
,
3N1O
,
3K7H
,
3K7I
,
3N1P
,
3K7J
,
3N1F
,
3N1M
PRO
Q14623
Orphanet
16250
PDB
3K7G
,
3N1O
,
3N1F
,
3K7H
,
3K7I
,
3N1P
,
3N1M
,
3K7J
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