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Relaxin-3 [extracellular region]
Stable Identifier
R-HSA-444822
Type
Complex
Species
Homo sapiens
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
RXFP3:Relaxin-3 [plasma membrane] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
RXFP4:RXFP4 ligands [plasma membrane] (Homo sapiens)
RXFP4 ligands [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
RXFP3:Relaxin-3 [plasma membrane] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
RXFP4:RXFP4 ligands [plasma membrane] (Homo sapiens)
RXFP4 ligands [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
RXFP3:Relaxin-3 [plasma membrane] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
RXFP4:RXFP4 ligands [plasma membrane] (Homo sapiens)
RXFP4 ligands [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
RXFP3:Relaxin-3 [plasma membrane] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
RXFP4:RXFP4 ligands [plasma membrane] (Homo sapiens)
RXFP4 ligands [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
RXFP3:Relaxin-3 [plasma membrane] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
RXFP4:RXFP4 ligands [plasma membrane] (Homo sapiens)
RXFP4 ligands [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
RXFP3:Relaxin-3 [plasma membrane] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
RXFP4:RXFP4 ligands [plasma membrane] (Homo sapiens)
RXFP4 ligands [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
RXFP1:Relaxin-2,Relaxin-3 [plasma membrane] (Homo sapiens)
Relaxin-2, Relaxin-3 [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
RXFP1:Relaxin-2,Relaxin-3 [plasma membrane] (Homo sapiens)
Relaxin-2, Relaxin-3 [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
RXFP1:Relaxin-2,Relaxin-3 [plasma membrane] (Homo sapiens)
Relaxin-2, Relaxin-3 [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
RXFP1:Relaxin-2,Relaxin-3 [plasma membrane] (Homo sapiens)
Relaxin-2, Relaxin-3 [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
RXFP1:Relaxin-2,Relaxin-3 [plasma membrane] (Homo sapiens)
Relaxin-2, Relaxin-3 [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gs [extracellular region] (Homo sapiens)
Relaxin-2, Relaxin-3 [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Relaxin receptors (Homo sapiens)
Relaxin 3 receptor 1 binds relaxin 3 (Homo sapiens)
RXFP3:Relaxin-3 [plasma membrane] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
Relaxin 3 receptor 2 binds relaxin 3 and INSL5 (Homo sapiens)
RXFP4 ligands [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
RXFP4:RXFP4 ligands [plasma membrane] (Homo sapiens)
RXFP4 ligands [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
Relaxin receptor 1 binds relaxin 2 and 3 (Homo sapiens)
RXFP1:Relaxin-2,Relaxin-3 [plasma membrane] (Homo sapiens)
Relaxin-2, Relaxin-3 [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
Relaxin-2, Relaxin-3 [extracellular region] (Homo sapiens)
Relaxin-3 [extracellular region] (Homo sapiens)
Participants
components
RLN3(119-142) [extracellular region]
(Homo sapiens)
RLN3(26-52) [extracellular region]
(Homo sapiens)
Participates
as a member of
Relaxin-2, Relaxin-3 [extracellular region] (Homo sapiens)
RXFP4 ligands [extracellular region] (Homo sapiens)
as an input of
Relaxin 3 receptor 1 binds relaxin 3 (Homo sapiens)
as a component of
RXFP3:Relaxin-3 [plasma membrane] (Homo sapiens)
Inferred To
Relaxin-3 [extracellular region]
(Bos taurus)
Relaxin-3 [extracellular region]
(Canis familiaris)
Relaxin-3 [extracellular region]
(Danio rerio)
Relaxin-3 [extracellular region]
(Mus musculus)
Relaxin-3 [extracellular region]
(Rattus norvegicus)
Relaxin-3 [extracellular region]
(Sus scrofa)
Relaxin-3 [extracellular region]
(Xenopus tropicalis)
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