EGF-TM7 receptors bind chondroitin sulphate

Stable Identifier
R-HSA-444773
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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EGF-TM7 receptors bind chondroitin sulphate
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The EGF-TM7 receptors are within the family B Adhesion (LNB) receptor subclass. They are characterised by long N-teminal extracellular domains containing multiple epidermal growth factor (EGF)-like domains. CD97 and EMR2 interact with the glycosaminoglycan chondroitin sulfate (CS).
Literature References
PubMed ID Title Journal Year
15498814 Expression of the largest CD97 and EMR2 isoforms on leukocytes facilitates a specific interaction with chondroitin sulfate on B cells

Kwakkenbos, MJ, Pouwels, W, Matmati, M, Stacey, M, Lin, HH, Gordon, S, van Lier, RA, Hamann, J

J Leukoc Biol 2005
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Orthologous Events
EGF-TM7 receptors bind chondroitin sulphate (Bos taurus)
EGF-TM7 receptors bind chondroitin sulphate (Caenorhabditis elegans)
EGF-TM7 receptors bind chondroitin sulphate (Canis familiaris)
EGF-TM7 receptors bind chondroitin sulphate (Danio rerio)
EGF-TM7 receptors bind chondroitin sulphate (Drosophila melanogaster)
EGF-TM7 receptors bind chondroitin sulphate (Mus musculus)
EGF-TM7 receptors bind chondroitin sulphate (Rattus norvegicus)
EGF-TM7 receptors bind chondroitin sulphate (Sus scrofa)
Authored
Jupe, S  (2009-10-23)
Reviewed
D'Eustachio, P  (2010-05-26)
Created
Jupe, S  (2009-10-26)
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