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CD97 [plasma membrane]
Stable Identifier
R-HSA-444764
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
CD97 antigen, CD97, CD97_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule membrane proteins (Homo sapiens)
Secretory granule membrane proteins [plasma membrane] (Homo sapiens)
CD97 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class B/2 (Secretin family receptors) (Homo sapiens)
CD97 binds CD55 (Homo sapiens)
CD55:CD97 [plasma membrane] (Homo sapiens)
CD97 [plasma membrane] (Homo sapiens)
CD97 [plasma membrane] (Homo sapiens)
EGF-TM7 receptors bind chondroitin sulphate (Homo sapiens)
EGF-7TMs [plasma membrane] (Homo sapiens)
CD97 [plasma membrane] (Homo sapiens)
EGF-7TMs:CHS [plasma membrane] (Homo sapiens)
EGF-7TMs [plasma membrane] (Homo sapiens)
CD97 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P48960 ADGRE5
Gene Names
ADGRE5, CD97
Chain
signal peptide:1-20, chain:21-835, chain:21-530, chain:531-835
Reference Genes
BioGPS Gene:976 ADGRE5
COSMIC (genes):ADGRE5 ADGRE5
CTD Gene:976 ADGRE5
dbSNP Gene:976 ADGRE5
ENSEMBL:ENSG00000123146 CD97
HGNC:1711 ADGRE5
KEGG:hsa:976 ADGRE5
Monarch:976 ADGRE5
NCBI Gene:976 ADGRE5
OMIM:601211 ADGRE5
UCSC:P48960 ADGRE5
Reference Transcript
RefSeq:XM_017027547.1 ADGRE5
RefSeq:NM_001025160.2 ADGRE5
RefSeq:NM_001784.4 ADGRE5
RefSeq:NM_078481.3 ADGRE5
Other Identifiers
11718680_a_at
11750408_a_at
16858970
202910_PM_s_at
202910_s_at
3441698
35625_at
3822669
3822670
3822671
3822672
3822673
3822674
3822675
3822676
3822679
3822680
3822681
3822682
3822683
3822684
3822685
3822686
3822687
3822688
3822690
3822691
3822692
3822693
3822694
3822695
3822697
3822698
3822699
3822700
3822701
3822702
3822703
3822704
3822705
3822706
3822708
3822710
3822711
3822712
3822713
3822714
3822715
3852905
3852906
3852907
3852909
3852910
3852911
3852920
3852921
3852922
3852923
3852927
8026300
976
A_23_P208579
A_23_P502312
A_23_P502314
GE610701
GE61077
GE85632
GO:0002376
GO:0004888
GO:0004930
GO:0005509
GO:0005515
GO:0005576
GO:0005886
GO:0005925
GO:0006954
GO:0006955
GO:0007155
GO:0007166
GO:0007186
GO:0007189
GO:0007267
GO:0016020
GO:0023052
GO:0030667
GO:0043226
GO:0060089
GO:0070062
HMNXSV003043779
ILMN_1673363
ILMN_1676718
ILMN_2413508
PH_hs_0000389
TC19000256.hg
U76764_s_at
g4502690_3p_a_at
Participates
as a component of
CD55:CD97 [plasma membrane] (Homo sapiens)
as an input of
CD97 binds CD55 (Homo sapiens)
as a member of
EGF-7TMs [plasma membrane] (Homo sapiens)
Secretory granule membrane proteins [plasma membrane] (Homo sapiens)
Other forms of this molecule
CD97(21-835) [secretory granule membrane]
Inferred To
Cirl [plasma membrane]
(Drosophila melanogaster)
Adgre5 [plasma membrane]
(Mus musculus)
Adgre5 [plasma membrane]
(Rattus norvegicus)
ADGRE5 [plasma membrane]
(Bos taurus)
ADGRE5 [plasma membrane]
(Canis familiaris)
ADGRE5 [plasma membrane]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
177
ENSEMBL
ENSP00000351413
,
ENSP00000242786
,
ENSP00000349918
,
ENST00000357355
,
ENST00000242786
,
ENST00000358600
OpenTargets
ENSG00000123146
HPA
ENSG00000123146-ADGRE5
PRO
P48960
Pharos - Targets
P48960
GlyGen
P48960
HMDB Protein
HMDBP10744
PDB
7YDH
,
7YDM
,
7YDJ
,
7YDP
,
2BOU
,
8IKL
,
7DO4
,
8IKJ
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O95858 TSPAN15
2
TSPAN15 [plasma membrane]
(R-HSA-9010043)
TSPAN15 [endoplasmic reticulum lumen]
(R-HSA-9010117)
0.527
4
UniProt:P0DTD8 NS7B
0.527
2
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