T1R1/T1R3 dimer is the umami taste receptor

Stable Identifier
R-HSA-444705
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
T1R1/T1R3 dimer is the umami taste receptor
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Dimers of the T1R1 and T1R3 receptors responds to the umami taste stimulus L-glutamate, signaling via the Gi family G-protein Gustducin (Caicedo et al. 2003).

Literature References
PubMed ID Title Journal Year
11917125 Human receptors for sweet and umami taste

Li, X, Staszewski, L, Xu, H, Durick, K, Zoller, M, Adler, E

Proc Natl Acad Sci U S A 2002
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
T1R1/T1R3 dimer is the umami taste receptor (Danio rerio)
T1R1/T1R3 dimer is the umami taste receptor (Gallus gallus)
T1R1/T1R3 dimer is the umami taste receptor (Mus musculus)
T1R1/T1R3 dimer is the umami taste receptor (Rattus norvegicus)
T1R1/T1R3 dimer is the umami taste receptor (Sus scrofa)
Authored
Jupe, S  (2009-10-23)
Reviewed
D'Eustachio, P  (2009-12-12)
Created
Jupe, S  (2009-10-26)