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GPR132 [plasma membrane]
Stable Identifier
R-HSA-444699
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
G2A, Probable G-protein coupled receptor 132, GP132_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
pH sensing receptors:H+ [plasma membrane] (Homo sapiens)
pH sensing receptors [plasma membrane] (Homo sapiens)
GPR132 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
pH sensing receptors:H+ [plasma membrane] (Homo sapiens)
pH sensing receptors [plasma membrane] (Homo sapiens)
GPR132 [plasma membrane] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
pH sensing receptors:H+ [plasma membrane] (Homo sapiens)
pH sensing receptors [plasma membrane] (Homo sapiens)
GPR132 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
pH sensing receptors:H+ [plasma membrane] (Homo sapiens)
pH sensing receptors [plasma membrane] (Homo sapiens)
GPR132 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
GPCRs that activate Gq/11 [plasma membrane] (Homo sapiens)
pH sensing receptors [plasma membrane] (Homo sapiens)
GPR132 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
pH sensing receptors:H+ [plasma membrane] (Homo sapiens)
pH sensing receptors [plasma membrane] (Homo sapiens)
GPR132 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Homo sapiens)
pH sensing receptors [plasma membrane] (Homo sapiens)
GPR132 [plasma membrane] (Homo sapiens)
pH sensing receptors:H+ [plasma membrane] (Homo sapiens)
pH sensing receptors [plasma membrane] (Homo sapiens)
GPR132 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UNW8 GPR132
Gene Names
GPR132, G2A
Chain
chain:1-380
Reference Genes
BioGPS Gene:29933 GPR132
COSMIC (genes):GPR132 GPR132
CTD Gene:29933 GPR132
dbSNP Gene:29933 GPR132
ENSEMBL:ENSG00000183484 GPR132
HGNC:17482 GPR132
KEGG:hsa:29933 GPR132
Monarch:29933 GPR132
NCBI Gene:29933 GPR132
OMIM:606167 GPR132
UCSC:Q9UNW8 GPR132
Reference Transcript
RefSeq:NM_001278696.1 GPR132
RefSeq:NM_001278694.1 GPR132
RefSeq:NM_001278695.1 GPR132
RefSeq:NM_013345.3 GPR132
Other Identifiers
11735793_a_at
11747649_a_at
11755482_x_at
16797224
221140_PM_s_at
221140_s_at
223887_3p_at
223887_PM_at
223887_at
29933
3581403
3581405
3581406
3581407
3581408
3581409
3581410
3581411
3581412
3581413
3581414
3581416
3581421
7981530
A_23_P128808
A_24_P201994
GE61761
GO:0000082
GO:0004930
GO:0005886
GO:0007186
GO:0010972
GO:0016020
GO:0060089
HMNXSV003026906
ILMN_1811171
PH_hs_0021043
TC14001564.hg
g13528716_3p_at
g13528716_3p_x_at
g7019386_3p_a_at
Participates
as a member of
pH sensing receptors [plasma membrane] (Homo sapiens)
Inferred To
GPR132 [plasma membrane]
(Bos taurus)
GPR132 [plasma membrane]
(Canis familiaris)
GPR132 [plasma membrane]
(Gallus gallus)
GPR132 [plasma membrane]
(Sus scrofa)
gpr132 [plasma membrane]
(Xenopus tropicalis)
Gpr132 [plasma membrane]
(Mus musculus)
Gpr132 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_001265623.1
,
NP_001265625.1
,
NP_001265624.1
,
NP_037477.1
Guide to Pharmacology - Targets
128
ENSEMBL
ENST00000392585
,
ENST00000539291
,
ENSP00000328818
,
ENSG00000183484
,
ENSP00000438094
,
ENST00000329797
,
ENSP00000376364
OpenTargets
ENSG00000183484
GeneCards
GPR132
HPA
ENSG00000183484-GPR132
PRO
Q9UNW8
Pharos - Targets
Q9UNW8
GlyGen
Q9UNW8
PDB
8HVI
,
8HQE
,
8HQN
,
8HQM
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