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C3AR1:C3a [plasma membrane]
Stable Identifier
R-HSA-444688
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
C3a receptor:C3a
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Cell recruitment (pro-inflammatory response) (Homo sapiens)
Purinergic signaling in leishmaniasis infection (Homo sapiens)
ATP translocates from cytosol to extracellular space (stimuated by C3AR1:C3a) (Homo sapiens)
C3AR1:C3a [plasma membrane] (Homo sapiens)
C3a receptor binds anaphylatoxin C3a (Homo sapiens)
C3AR1:C3a [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Complement cascade (Homo sapiens)
Regulation of Complement cascade (Homo sapiens)
C3a receptor binds anaphylatoxin C3a (Homo sapiens)
C3AR1:C3a [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
C3AR1:C3a [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
C3AR1:C3a [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
C3AR1:C3a [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
C3AR1:C3a [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
C3AR1:C3a [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
C3AR1:C3a [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
C3a receptor binds anaphylatoxin C3a (Homo sapiens)
C3AR1:C3a [plasma membrane] (Homo sapiens)
Participants
components
C3a [extracellular region]
(Homo sapiens)
C3AR1 [plasma membrane]
(Homo sapiens)
Participates
as an output of
C3a receptor binds anaphylatoxin C3a (Homo sapiens)
as a member of
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
This entity regulates
Positively
ATP translocates from cytosol to extracellular space (stimuated by C3AR1:C3a)
(Homo sapiens)
Inferred To
C3AR1:C3a [plasma membrane]
(Bos taurus)
C3AR1:C3a [plasma membrane]
(Canis familiaris)
C3AR1:C3a [plasma membrane]
(Gallus gallus)
C3AR1:C3a [plasma membrane]
(Mus musculus)
C3AR1:C3a [plasma membrane]
(Rattus norvegicus)
C3AR1:C3a [plasma membrane]
(Xenopus tropicalis)
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