Reactome | CXCR5 binds CXCL13

CXCR5 binds CXCL13

Stable Identifier

R-HSA-444523

Type

Reaction [binding]

Species

Homo sapiens

Compartment

extracellular region, plasma membrane

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR ligand binding (Homo sapiens)
    - Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
      - Peptide ligand-binding receptors (Homo sapiens)
        
        Chemokine receptors bind chemokines (Homo sapiens)
        
        CXCR5 binds CXCL13 (Homo sapiens)

General

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CXC-Chemokine receptor 5 (CXCR5) was originally called Burkitts Lymphoma receptor 1 after the source tissue. The primary ligand for this receptor is CXCL13 (B-cell attracting chemokine 1 also known as B-lymphocyte chemoattractant).

Literature References

PubMed ID	Title	Journal	Year
9463416	B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5 Legler, DF, Loetscher, M, Roos, RS, Clark-Lewis, I, Baggiolini, M, Moser, B	J Exp Med	1998