Reactome | HEBP1(1-21) [extracellular region]

HEBP1(1-21) [extracellular region]

Stable Identifier

R-HSA-444480

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

F2L, Heme-binding protein 1, HEBP1, HEBP1_HUMAN

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR downstream signalling (Homo sapiens)
    - G alpha (i) signalling events (Homo sapiens)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
      - The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
  - GPCR ligand binding (Homo sapiens)
    - Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
      - Peptide ligand-binding receptors (Homo sapiens)
        
        Formyl peptide receptors bind formyl peptides and many other ligands (Homo sapiens)
        
        FPRL2 receptor binds a wide range of ligands (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
        
        FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9NRV9 HEBP1

Gene Names

HEBP1, HBP

Chain

chain:1-189

Reference Genes

BioGPS Gene:50865 HEBP1

COSMIC (genes):HEBP1 HEBP1

CTD Gene:50865 HEBP1

dbSNP Gene:50865 HEBP1

ENSEMBL:ENSG00000013583 HEBP1

HGNC:17176 HEBP1

KEGG Gene (Homo sapiens):50865 HEBP1

Monarch:50865 HEBP1

NCBI Gene:50865 HEBP1

OMIM:605826 HEBP1

UCSC:Q9NRV9 HEBP1

Reference Transcript

RefSeq:NM_015987.4 HEBP1

Other Identifiers

0006940184

11758130_s_at

16761663

218450_at

3445124

3445125

3445126

3445127

3445135

3445137

3445138

3445139

48093_at

50865

7961390

A_23_P117082

GE58639

GO:0003674

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0007165

GO:0007186

GO:0007623

GO:0008150

GO:0020037

GO:0043226

GO:0070062

HMNXSV003026544

ILMN_1802557

PH_hs_0015307

TC12001259.hg

g7705404_3p_at

Participates

as a member of

FPR3 ligands [extracellular region] (Homo sapiens)

Inferred To

HEBP1 [extracellular region] (Gallus gallus)

HEBP1(1-21) [extracellular region] (Xenopus tropicalis)

Hebp1 [extracellular region] (Mus musculus)

Hebp1 [extracellular region] (Rattus norvegicus)

Cross References

RefSeq

NP_057071.2

OpenTargets

ENSG00000013583

HPA

ENSG00000013583-HEBP1

GeneCards

Q9NRV9

Ensembl

ENSP00000014930, ENST00000014930, ENSG00000013583

PRO

Q9NRV9

Pharos - Targets

Q9NRV9

HMDB Protein

HMDBP08654