Reactome | HEBP1(1-21) [extracellular region]

HEBP1(1-21) [extracellular region]

Stable Identifier

R-HSA-444480

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

F2L, Heme-binding protein 1, HEBP1, HEBP1_HUMAN

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR downstream signalling (Homo sapiens)
    - G alpha (i) signalling events (Homo sapiens)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
      - The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
        
        FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
        
        Ligands of GPCRs that activate Gi [extracellular region] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
  - GPCR ligand binding (Homo sapiens)
    - Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
      - Peptide ligand-binding receptors (Homo sapiens)
        
        Formyl peptide receptors bind formyl peptides and many other ligands (Homo sapiens)
        
        FPRL2 receptor binds a wide range of ligands (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)
        
        FPR3:FPR3 ligands [plasma membrane] (Homo sapiens)
        
        FPR3 ligands [extracellular region] (Homo sapiens)
        
        HEBP1(1-21) [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9NRV9 HEBP1

Gene Names

HEBP1, HBP

Chain

chain:1-189

Reference Genes

BioGPS Gene:50865 HEBP1

COSMIC (genes):HEBP1 HEBP1

CTD Gene:50865 HEBP1

dbSNP Gene:50865 HEBP1

ENSEMBL:ENSG00000013583 HEBP1

ENSEMBL_homo_sapiens_GENE:ENSG00000013583 HEBP1

HGNC:17176 HEBP1

KEGG Gene (Homo sapiens):50865 HEBP1

Monarch:50865 HEBP1

NCBI Gene:50865 HEBP1

OMIM:605826 HEBP1

UCSC:Q9NRV9 HEBP1

Reference Transcript

RefSeq:NM_015987.4 HEBP1

Other Identifiers

0006940184

11758130_s_at

16761663

218450_at

3445124

3445125

3445126

3445127

3445135

3445137

3445138

3445139

48093_at

50865

56417

75277

7961390

A0A024RAS8

A_23_P117082

AAD32098

AAF89618

AAH16277

AAP35958

BAF82566

CCDS31749

EAW96295

EAW96296

ENSG00000013583

ENSP00000014930

ENST00000014930

EntrezGene:50865

F5GWX2

g7705404_3p_at

GE58639

GO:0003674

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005623

GO:0005737

GO:0005829

GO:0007165

GO:0007186

GO:0007623

GO:0008150

GO:0020037

GO:0043226

GO:0070062

HEBP1

HEBP1-201

HGNC:17176

HPA056417

HPA075277

ILMN_1802557

IPR006917

IPR011256

MIM:605826

NM_015987

NP_057071

PF04832

PH_hs_0015307

TC12001259.hg

uc001rbd.4

UPI0000038D71

Participant Of

hasMember

FPR3 ligands [extracellular region]

Inferred To

Homologues of HEBP1(1-21) [extracellular region] (Bos taurus)

Homologues of HEBP1(1-21) [extracellular region] (Danio rerio)

Homologues of HEBP1(1-21) [extracellular region] (Taeniopygia guttata)

HEBP1(1-21) [extracellular region] (Bos taurus)

HEBP1(1-21) [extracellular region] (Canis familiaris)

HEBP1(1-21) [extracellular region] (Danio rerio)

HEBP1(1-21) [extracellular region] (Gallus gallus)

HEBP1(1-21) [extracellular region] (Mus musculus)

HEBP1(1-21) [extracellular region] (Rattus norvegicus)

HEBP1(1-21) [extracellular region] (Sus scrofa)

HEBP1(1-21) [extracellular region] (Taeniopygia guttata)

HEBP1(1-21) [extracellular region] (Xenopus tropicalis)

Cross References

RefSeq

NP_057071.2

OpenTargets

ENSG00000013583

GeneCards

Q9NRV9

PRO

Q9NRV9

HMDB Protein

HMDBP08654