MLNR (GPR38) is a receptor for motilin

Stable Identifier
R-HSA-444208
Type
Reaction
Species
Homo sapiens
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Motilin is a 22-amino acid peptide hormone expressed throughout the gastrointestinal (GI) tract of humans and other species. It affects gastric motility by stimulating interdigestive antrum and duodenal contractions. The receptor protein is known as motilin receptor, derived from the gene MLNR (first identified as GPR38).

Literature References
PubMed ID Title Journal Year
10381885 Receptor for motilin identified in the human gastrointestinal system

Van Der Ploeg, LH, Tan, CP, Hreniuk, DL, Palyha, OC, Smith, RG, O'Neill, G, Evans, J, Pong, SS, Nargund, R, Austin, CP, Figueroa, D, Stocco, R, Bakshi, R, Cascieri, MA, MacNeil, D, Feighner, SD, Kargman, S, Patchett, AA, Abramovitz, M, McKee, KK, Howard, AD

Science 1999
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