CaMKII binds activated calmodulin

Stable Identifier
R-HSA-442725
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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CaMKII is fully activated upon binding to the complex of calcium and calmodulin (CALM1:4xCa2+), which forms upon influx of calcium ions through activated NMDA receptors. Autophosphorylation increases the affinity of CaMKII for the active calmodulin (CALM1:4xCa2+) (Meyer et al. 1992).

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