CREB1 phosphorylation through the activation of Adenylate Cyclase

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R-HSA-442720
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Pathway
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Homo sapiens
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Ca2+ influx through activated NMDA receptors in the post synaptic neurons activates adenylate cyclase-mediated signal transduction, leading to the activation of PKA and phosphorylation and activation of CREB1 induced transcription (Masada et al. 2012, Chetkovich et al. 1991, Chetkovich and Sweatt 1993

Literature References
PubMed ID Title Journal Year
19244110 RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway

James, MA, Lu, Y, Liu, Y, Vikis, HG, You, M

Cancer Res 2009
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Orthologous Events
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BioModels Database
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