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SLC39A14 [plasma membrane]
Stable Identifier
R-HSA-442375
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
ZIP14, Zinc transporter ZIP14, S39AE_HUMAN
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Metal ion SLC transporters (Homo sapiens)
Zinc transporters (Homo sapiens)
Zinc influx into cells by the SLC39 gene family (Homo sapiens)
ZIP6 and ZIP14 mediate zinc influx into cells (Homo sapiens)
ZIP6/ZIP14 [plasma membrane] (Homo sapiens)
SLC39A14 [plasma membrane] (Homo sapiens)
ZIP8 mediates zinc influx into cells (Homo sapiens)
SLC39A8-like proteins [plasma membrane] (Homo sapiens)
SLC39A14 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15043 SLC39A14
Gene Names
SLC39A14, KIAA0062, ZIP14
Chain
signal peptide:1-30, chain:31-492
Reference Genes
BioGPS Gene:23516 SLC39A14
COSMIC (genes):SLC39A14 SLC39A14
CTD Gene:23516 SLC39A14
dbSNP Gene:23516 SLC39A14
ENSEMBL:ENSG00000104635 SLC39A14
ENSEMBL_homo_sapiens_GENE:ENSG00000104635.15 SLC39A14
HGNC:20858 SLC39A14
KEGG Gene (Homo sapiens):23516 SLC39A14
Monarch:23516 SLC39A14
NCBI Gene:23516 SLC39A14
OMIM:608736 SLC39A14
UCSC:Q15043 SLC39A14
Reference Transcript
RefSeq:XM_011544478.2 SLC39A14
RefSeq:XM_006716324.2 SLC39A14
RefSeq:NM_001128431.2 SLC39A14
RefSeq:XM_017013295.1 SLC39A14
RefSeq:XM_017013294.1 SLC39A14
RefSeq:NM_015359.4 SLC39A14
RefSeq:NM_001135153.1 SLC39A14
RefSeq:XM_005273466.4 SLC39A14
RefSeq:XM_005273465.2 SLC39A14
Other Identifiers
11736570_a_at
11737909_at
11737910_x_at
11739083_a_at
1555433_PM_at
1555433_at
1555434_PM_a_at
1555434_a_at
17066601
212110_PM_at
212110_at
23516
3089361
3089362
3089372
3089373
3089375
3089381
3089382
3089383
3089384
3089385
3089386
3089387
3089388
3089389
3089390
3089391
3089392
3089393
38797_at
8145122
A_23_P59950
A_24_P333479
A_24_P383356
D31887_at
GE57170
GO:0002062
GO:0005215
GO:0005381
GO:0005384
GO:0005385
GO:0005515
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005886
GO:0005975
GO:0006094
GO:0006811
GO:0006826
GO:0006829
GO:0006882
GO:0008286
GO:0010008
GO:0010817
GO:0015086
GO:0015093
GO:0015296
GO:0015701
GO:0016020
GO:0016323
GO:0016324
GO:0016328
GO:0023052
GO:0030001
GO:0030154
GO:0031410
GO:0031901
GO:0031902
GO:0032869
GO:0033212
GO:0034755
GO:0043226
GO:0045745
GO:0046873
GO:0048856
GO:0051344
GO:0055065
GO:0055071
GO:0055085
GO:0070574
GO:0071333
GO:0071421
GO:0071577
GO:0071578
GO:0098656
GO:0098662
GO:0098739
GO:0140410
HMNXSV003014944
HMNXSV003054861
Hs.89868.0.A1_3p_at
Hs2.89868.1.S1_3p_at
Hs2.89868.1.S1_3p_x_at
ILMN_1764629
PH_hs_0028146
TC08000170.hg
Participates
as a member of
ZIP6/ZIP14 [plasma membrane] (Homo sapiens)
as a candidate of
SLC39A8-like proteins [plasma membrane] (Homo sapiens)
Inferred To
SLC39A14 [plasma membrane]
(Bos taurus)
SLC39A14 [plasma membrane]
(Canis familiaris)
SLC39A14 [plasma membrane]
(Gallus gallus)
SLC39A14 [plasma membrane]
(Sus scrofa)
zipt-15 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SLC39A14 [plasma membrane]
(Caenorhabditis elegans)
slc39a14 [plasma membrane]
(Danio rerio)
slc39a14 [plasma membrane]
(Xenopus tropicalis)
zipt-16 [plasma membrane]
(Caenorhabditis elegans)
Slc39a14 [plasma membrane]
(Mus musculus)
Slc39a14 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
XP_011542780.1
,
NP_001121903.1
,
XP_005273522.1
,
XP_005273523.1
,
NP_056174.2
,
XP_016868783.1
,
XP_006716387.1
,
NP_001128625.1
,
XP_016868784.1
Guide to Pharmacology - Targets
1193
OpenTargets
ENSG00000104635
HPA
ENSG00000104635-SLC39A14
GeneCards
Q15043
Ensembl
ENST00000381237
,
ENSG00000104635
,
ENSP00000352779
,
ENSP00000289952
,
ENSP00000370635
,
ENST00000289952
,
ENSP00000240095
,
ENST00000240095
,
ENST00000359741
PRO
Q15043
Pharos - Targets
Q15043
Orphanet
27526
HMDB Protein
HMDBP08690
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
7
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