E2F1/3:DP1/2 binds NOTCH1 promoter

Stable Identifier
R-HSA-4395231
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
E2F1 and E2F3 are able to bind to the NOTCH1 promoter and activate NOTCH1 transcription (Viatour et al. 2011).
Literature References
PubMed ID Title Journal Year
21875955 Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway

Saddic, LA, Zmoos, AF, Sylvester, KG, Ehmer, U, Sage, J, Dorrell, C, Lin, C, Viatour, P, Grompe, M, Thorgeirsson, SS, Mazur, PK, Schaffer, BE, Andersen, JB, Vogel, H, Ostermeier, A

J Exp Med 2011
Participants
Participates
Authored
Reviewed
Created
Cite Us!