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SLC11A1 [late endosome membrane]
Stable Identifier
R-HSA-437103
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
late endosome membrane
Synonyms
NRAMP1, Natural resistance-associated macrophage protein 1, NRAM1_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Antimicrobial peptides (Homo sapiens)
Ion influx/efflux at host-pathogen interface (Homo sapiens)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Homo sapiens)
SLC11A1 [late endosome membrane] (Homo sapiens)
ROS and RNS production in phagocytes (Homo sapiens)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Homo sapiens)
SLC11A1 [late endosome membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Metal ion SLC transporters (Homo sapiens)
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Homo sapiens)
SLC11A1 [late endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P49279 SLC11A1
Gene Names
SLC11A1, LSH, NRAMP, NRAMP1
Chain
chain:1-550
Reference Genes
BioGPS Gene:6556 SLC11A1
COSMIC (genes):SLC11A1 SLC11A1
CTD Gene:6556 SLC11A1
dbSNP Gene:6556 SLC11A1
ENSEMBL:ENSG00000018280.17 SLC11A1
HGNC:10907 SLC11A1
KEGG Gene (Homo sapiens):6556 SLC11A1
Monarch:6556 SLC11A1
NCBI Gene:6556 SLC11A1
OMIM:600266 SLC11A1
UCSC:P49279 SLC11A1
Reference Transcript
RefSeq:XM_006712709.3 SLC11A1
RefSeq:XM_005246793.3 SLC11A1
RefSeq:NM_000578.3 SLC11A1
RefSeq:XM_006712710.3 SLC11A1
RefSeq:XM_005246794.3 SLC11A1
RefSeq:XM_017004766.1 SLC11A1
Other Identifiers
11727842_at
11727843_a_at
11747774_a_at
11748920_x_at
16890837
210422_PM_x_at
210422_x_at
210423_PM_s_at
210423_s_at
217473_PM_x_at
217473_x_at
217507_PM_at
217507_at
2527748
2527751
2527752
2527754
2527755
2527756
2527757
2527759
2527762
2527763
2527764
2527767
2527769
2527770
2527773
2527774
2527775
2527776
2527777
2527778
2527779
2527781
2527782
2527783
2527785
2527787
38596_i_at
38597_f_at
38598_at
6556
8048283
A_23_P39665
A_33_P3317005
A_33_P3702055
D50402_at
GE61504
GE87252
GO:0001818
GO:0001819
GO:0002309
GO:0002376
GO:0002606
GO:0002827
GO:0005215
GO:0005381
GO:0005384
GO:0005764
GO:0005768
GO:0005770
GO:0005773
GO:0005886
GO:0006351
GO:0006355
GO:0006811
GO:0006826
GO:0006828
GO:0006876
GO:0006879
GO:0006909
GO:0006954
GO:0007035
GO:0009617
GO:0010008
GO:0010628
GO:0015086
GO:0015707
GO:0016020
GO:0016071
GO:0016192
GO:0019730
GO:0030001
GO:0030670
GO:0031410
GO:0031902
GO:0032147
GO:0032496
GO:0032729
GO:0034341
GO:0034755
GO:0036211
GO:0042060
GO:0042116
GO:0042742
GO:0042803
GO:0042832
GO:0043226
GO:0045342
GO:0045454
GO:0045730
GO:0045944
GO:0046873
GO:0046915
GO:0048002
GO:0048255
GO:0050766
GO:0050829
GO:0051139
GO:0051649
GO:0055065
GO:0055072
GO:0055085
GO:0060586
GO:0070574
GO:0070821
GO:0071421
GO:0098542
GO:0101003
GO:1902600
GO:1903826
HMNXSV003027916
Hs.265982.0.A1_3p_at
ILMN_1735737
ILMN_1741165
L38593_s_at
PH_hs_0040091
g600219_3p_a_at
Other forms of this molecule
SLC11A1 [tertiary granule membrane]
SLC11A1 [plasma membrane]
SLC11A1 [ficolin-1-rich granule membrane]
Inferred To
smf-1 [late endosome membrane]
(Caenorhabditis elegans)
slc11a1 [late endosome membrane]
(Xenopus tropicalis)
Mvl [late endosome membrane]
(Drosophila melanogaster)
smf-3 [late endosome membrane]
(Caenorhabditis elegans)
Homologues of SLC11A1 [late endosome membrane]
(Caenorhabditis elegans)
nramp1 [late endosome membrane]
(Dictyostelium discoideum)
smf-2 [late endosome membrane]
(Caenorhabditis elegans)
SLC11A1 [late endosome membrane]
(Bos taurus)
SLC11A1 [late endosome membrane]
(Canis familiaris)
SLC11A1 [late endosome membrane]
(Gallus gallus)
SLC11A1 [late endosome membrane]
(Plasmodium falciparum)
SLC11A1 [late endosome membrane]
(Sus scrofa)
Slc11a1 [late endosome membrane]
(Mus musculus)
Slc11a1 [late endosome membrane]
(Rattus norvegicus)
Cross References
RefSeq
XP_005246850.1
,
NP_000569.3
,
XP_006712773.1
,
XP_006712772.1
,
XP_016860255.1
,
XP_005246851.1
Guide to Pharmacology - Targets
966
OpenTargets
ENSG00000018280
GeneCards
P49279
HPA
ENSG00000018280-SLC11A1
Ensembl
ENST00000233202
,
ENSP00000233202
,
ENSG00000018280
ZINC target
P49279
PRO
P49279
Pharos - Targets
P49279
Orphanet
17203
HMDB Protein
HMDBP08680
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