Reactome | SLC30A3 [synaptic vesicle membrane]

SLC30A3 [synaptic vesicle membrane]

Stable Identifier

R-HSA-437087

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

synaptic vesicle membrane

Synonyms

ZnT3, Zinc transporter 3, ZNT3_HUMAN

Locations in the PathwayBrowser

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Transport of small molecules (Homo sapiens)

- SLC-mediated transmembrane transport (Homo sapiens)
  - Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
    - Metal ion SLC transporters (Homo sapiens)
      - Zinc transporters (Homo sapiens)
        
        Zinc efflux and compartmentalization by the SLC30 family (Homo sapiens)
        
        ZnT3 transports zinc into synaptic vesicles (Homo sapiens)
        
        SLC30A3-like Protein [synaptic vesicle membrane] (Homo sapiens)
        
        SLC30A3 [synaptic vesicle membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q99726 SLC30A3

Gene Names

SLC30A3, ZNT3

Chain

chain:1-388

Reference Genes

BioGPS Gene:7781 SLC30A3

COSMIC (genes):SLC30A3 SLC30A3

CTD Gene:7781 SLC30A3

dbSNP Gene:7781 SLC30A3

ENSEMBL:ENSG00000115194 SLC30A3

HGNC:11014 SLC30A3

KEGG:hsa:7781 SLC30A3

Monarch:7781 SLC30A3

NCBI Gene:7781 SLC30A3

OMIM:602878 SLC30A3

UCSC:Q99726 SLC30A3

Reference Transcript

Other Identifiers

11729403_a_at

11748833_a_at

16895712

207035_PM_at

207035_at

2545614

2545615

2545616

2545617

2545618

2545619

2545620

2545621

2545622

2545623

2545624

2545625

2545626

2545627

2545628

2545629

2545632

2545633

2545634

2545635

2545636

34457_at

7781

8051050

A_23_P302568

GE80113

GO:0005215

GO:0005385

GO:0005515

GO:0005737

GO:0005764

GO:0005765

GO:0005768

GO:0005770

GO:0005773

GO:0005886

GO:0006812

GO:0006829

GO:0008021

GO:0008324

GO:0010043

GO:0015297

GO:0016020

GO:0030672

GO:0031410

GO:0031902

GO:0043005

GO:0043226

GO:0045202

GO:0046872

GO:0051050

GO:0055085

GO:0062111

GO:0071577

GO:0097457

GO:0098686

GO:0098978

GO:0099180

GO:0140916

GO:1990742

HMNXSV003043434

ILMN_1805807

PH_hs_0031533

U76010_at

g4508042_3p_at

Participates

as a member of

SLC30A3-like Protein [synaptic vesicle membrane] (Homo sapiens)

Cross References

Guide to Pharmacology - Targets

1123

ENSEMBL

ENSP00000233535, ENST00000233535

OpenTargets

ENSG00000115194

HPA

ENSG00000115194-SLC30A3

PRO

Q99726

Pharos - Targets

Q99726

HMDB Protein

HMDBP12038

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BRI3 SLC30A2	2	SLC30A2 [endosome membrane] (R-HSA-435363) SLC30A2 [synaptic vesicle membrane] (R-HSA-4084714)	0.674	7
UniProt:Q3KNW5 SLC10A6	1	SLC10A6 [plasma membrane] (R-HSA-433091)	0.556	3
UniProt:O95470 SGPL1	1	PXLP-SGPL1 [endoplasmic reticulum membrane] (R-HSA-428661)	0.556	3
UniProt:Q8IWU4 SLC30A8	2	SLC30A8 [Golgi membrane] (R-HSA-9817561) SLC30A8 [secretory granule membrane] (R-HSA-437106)	0.556	3
UniProt:Q7Z5P4 HSD17B13	1	HSD17B13 [cytosol] (R-HSA-8862029)	0.556	3
UniProt:Q6XR72 SLC30A10	1	SLC30A10 [plasma membrane] (R-HSA-437102)	0.524	3

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