ZnT1 mediates the efflux of zinc from the cell

Stable Identifier
R-HSA-435366
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The human gene SLC30A1 encodes the zinc transporter ZnT1. It is widely expressed throughout the body and it's expression is regulated by zinc. ZnT1 is the only member of the SLC30 gene family that is located on the plasma membrane and mediates the transport of zinc out of the cell (Devergnas S et al, 2004).

Literature References
PubMed ID Title Journal Year
15276077 Differential regulation of zinc efflux transporters ZnT-1, ZnT-5 and ZnT-7 gene expression by zinc levels: a real-time RT-PCR study

Devergnas, S, Chimienti, F, Naud, N, Pennequin, A, Coquerel, Y, Chantegrel, J, Favier, A, Seve, M

Biochem Pharmacol 2004
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
zinc ion transmembrane transporter activity of SLC30A1 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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