Reactome | PICALM [Golgi membrane]

PICALM [Golgi membrane]

Stable Identifier

R-HSA-434341

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Phosphatidylinositol-binding clathrin assembly protein, PICAL_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q13492 PICALM

Gene Names

PICALM, CALM

Chain

initiator methionine:, chain:2-652

Reference Genes

BioGPS Gene:8301 PICALM

COSMIC (genes):PICALM PICALM

CTD Gene:8301 PICALM

dbSNP Gene:8301 PICALM

ENSEMBL:ENSG00000073921 PICALM

HGNC:15514 PICALM

KEGG:hsa:8301 PICALM

Monarch:8301 PICALM

NCBI Gene:8301 PICALM

OMIM:603025 PICALM

UCSC:Q13492 PICALM

Reference Transcript

Participates

as a candidate of

Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)

Other forms of this molecule

PICALM [cytoplasmic vesicle membrane]

PICALM [cytosol]

Inferred To

clmA [Golgi membrane] (Dictyostelium discoideum)

PICALM [Golgi membrane] (Bos taurus)

PICALM [Golgi membrane] (Canis familiaris)

PICALM [Golgi membrane] (Gallus gallus)

PICALM [Golgi membrane] (Sus scrofa)

lap [Golgi membrane] (Drosophila melanogaster)

YAP1802 [Golgi membrane] (Saccharomyces cerevisiae)

unc-11 [Golgi membrane] (Caenorhabditis elegans)

Homologues of PICALM [Golgi membrane] (Saccharomyces cerevisiae)

Picalm [Golgi membrane] (Mus musculus)

Picalm [Golgi membrane] (Rattus norvegicus)

YAP1801 [Golgi membrane] (Saccharomyces cerevisiae)

Cross References

ENSEMBL

ENSP00000377015, ENSP00000434884, ENST00000526033, ENST00000356360, ENSP00000348718, ENST00000528398, ENSG00000073921, ENST00000393346, ENST00000532317, ENSP00000436958, ENSP00000433846

OpenTargets

ENSG00000073921

GeneCards

PICALM

HPA

ENSG00000073921-PICALM

PRO

Q13492

Pharos - Targets

Q13492

GlyGen

Q13492

Orphanet

PICALM

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.645	8
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	8
UniProt:P42566 EPS15	2	p-Y849 EPS15 [cytosol] (R-HSA-8867028) EPS15 [cytosol] (R-HSA-182920)	0.59	2
UniProt:Q9NYZ3 GTSE1	4	GTSE1 [cytosol] (R-HSA-8852264) p-S435-GTSE1 [cytosol] (R-HSA-8852316) p-S435-GTSE1 [nucleoplasm] (R-HSA-8852332) p-T513,T526-GTSE1 [cytosol] (R-HSA-8852308)	0.527	2
UniProt:O00443 PIK3C2A	3	PIK3C2A [cytosol] (R-HSA-1604624) PIK3C2A [cytoplasmic vesicle membrane] (R-HSA-432683) PIK3C2A [Golgi membrane] (R-HSA-432679)	0.527	2

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