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AP3B1 [Golgi membrane]
Stable Identifier
R-HSA-434335
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
AP-3 complex subunit beta-1, AP3B1_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Golgi Associated Vesicle Biogenesis (Homo sapiens)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
AP3B1 [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
AP3B1 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Coat Assembly (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
AP3B1 [Golgi membrane] (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
AP3B1 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Vesicle Scission (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
AP3B1 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00203 AP3B1
Gene Names
AP3B1, ADTB3A
Chain
chain:1-1094
Reference Genes
BioGPS Gene:8546 AP3B1
COSMIC (genes):AP3B1 AP3B1
CTD Gene:8546 AP3B1
dbSNP Gene:8546 AP3B1
ENSEMBL:ENSG00000132842 AP3B1
HGNC:566 AP3B1
KEGG Gene (Homo sapiens):8546 AP3B1
Monarch:8546 AP3B1
NCBI Gene:8546 AP3B1
OMIM:603401 AP3B1
UCSC:O00203 AP3B1
Reference Transcript
RefSeq:NM_003664.4 AP3B1
RefSeq:NM_001271769.1 AP3B1
Other Identifiers
0006040040
11719294_at
11719295_a_at
16997457
203141_s_at
203142_s_at
2863754
2863755
2863760
2863763
2863767
2863769
2863788
2863793
2863796
2863797
2863798
2863800
2863801
2863802
2863804
2863805
2863807
2863808
2863809
2863810
2863813
2863814
2863815
2863817
2863818
2863819
2863821
2863822
2863823
2863825
2863827
2863832
2863833
2863834
32039_at
8112772
8546
89136_at
A_23_P136635
GE81313
GO:0000003
GO:0000902
GO:0002244
GO:0002376
GO:0003016
GO:0003674
GO:0005575
GO:0005622
GO:0005737
GO:0005739
GO:0005764
GO:0005765
GO:0005773
GO:0005794
GO:0006605
GO:0006622
GO:0006810
GO:0006882
GO:0006886
GO:0006950
GO:0006954
GO:0007005
GO:0007034
GO:0007040
GO:0007155
GO:0007283
GO:0007338
GO:0007596
GO:0008089
GO:0008150
GO:0009058
GO:0015031
GO:0016020
GO:0016182
GO:0016192
GO:0019882
GO:0019899
GO:0019903
GO:0030117
GO:0030123
GO:0030131
GO:0030154
GO:0030324
GO:0030665
GO:0030705
GO:0030742
GO:0030851
GO:0031410
GO:0032438
GO:0032991
GO:0034394
GO:0034641
GO:0042592
GO:0042789
GO:0043226
GO:0043473
GO:0045202
GO:0048007
GO:0048490
GO:0048856
GO:0048872
GO:0050790
GO:0051138
GO:0060155
GO:0060425
GO:0061024
GO:0090152
GO:0098773
GO:1904115
Hs.155172.0.S1_3p_a_at
ILMN_1768867
PH_hs_0026120
TC05001513.hg
U91931_at
g4501974_3p_a_at
Participant Of
hasCandidate
Golgi-associated Vesicle Destined Cargo [Golgi membrane]
Other forms of this molecule
AP3B1 [cytoplasmic vesicle membrane]
AP3B1-BRAF fusion [cytosol]
p-AP3B1-BRAF fusion [cytosol]
Inferred To
ap3b-2 [Golgi membrane] (Dictyostelium discoideum)
APL6 [Golgi membrane] (Saccharomyces cerevisiae)
apb-3 [Golgi membrane] (Caenorhabditis elegans)
Ap3b1 [Golgi membrane] (Mus musculus)
Ap3b1 [Golgi membrane] (Rattus norvegicus)
rb [Golgi membrane] (Drosophila melanogaster)
AP3B1 [Golgi membrane] (Canis familiaris)
AP3B1 [Golgi membrane] (Gallus gallus)
AP3B1 [Golgi membrane] (Plasmodium falciparum)
AP3B1 [Golgi membrane] (Sus scrofa)
apl6 [Golgi membrane] (Schizosaccharomyces pombe)
Cross References
RefSeq
NP_001258698.1
,
NP_003655.3
OpenTargets
ENSG00000132842
HPA
ENSG00000132842-AP3B1
GeneCards
O00203
Ensembl
ENST00000519295
,
ENSP00000430597
,
ENST00000255194
,
ENSG00000132842
,
ENSP00000255194
PRO
O00203
Orphanet
15934
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
6
UniProt:P37840 SNCA
4
SNCA [extracellular region]
(R-HSA-976954)
SNCA A30P [cytosol]
(R-HSA-5658569)
SNCA [cytosol]
(R-HSA-5658500)
Ub-SNCA [cytosol]
(R-HSA-5660754)
0.556
3
UniProt:Q96CV9 OPTN
4
OPTN [Golgi membrane]
(R-HSA-2161111)
OPTN [recycling endosome membrane]
(R-HSA-8854141)
p-S177-OPTN [nucleoplasm]
(R-HSA-2562595)
p-S177-OPTN [cytosol]
(R-HSA-2562525)
0.556
3
UniProt:P0DTC4 E
9
nascent E [endoplasmic reticulum lumen]
(R-COV-9694312)
N-glycan E [endoplasmic reticulum lumen]
(R-COV-9694754)
3xPalmC-E [endoplasmic reticulum lumen]
(R-COV-9694305)
Ub-3xPalmC-E [endoplasmic reticulum lumen]
(R-COV-9694423)
Ub-3xPalmC-E [endoplasmic reticulum membrane]
(R-COV-9694465)
Ub-3xPalmC-E [Golgi membrane]
(R-COV-9694687)
Ub-3xPalmC-E [endocytic vesicle membrane]
(R-COV-9698422)
Ub-3xPalmC-E [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9698420)
Ub-3xPalmC-E [virion membrane]
(R-COV-9698416)
0.527
2
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