Reactome | AP3B1 [Golgi membrane]

AP3B1 [Golgi membrane]

Stable Identifier

R-HSA-434335

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

AP-3 complex subunit beta-1, AP3B1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O00203 AP3B1

Gene Names

AP3B1, ADTB3A

Chain

chain:1-1094

Reference Genes

BioGPS Gene:8546 AP3B1

COSMIC (genes):AP3B1 AP3B1

CTD Gene:8546 AP3B1

dbSNP Gene:8546 AP3B1

ENSEMBL:ENSG00000132842 AP3B1

ENSEMBL:ENSG00000132842.15 AP3B1

HGNC:566 AP3B1

KEGG Gene (Homo sapiens):8546 AP3B1

Monarch:8546 AP3B1

NCBI Gene:8546 AP3B1

OMIM:603401 AP3B1

UCSC:O00203 AP3B1

Reference Transcript

Other Identifiers

11719294_at

11719295_a_at

16997457

203141_PM_s_at

203141_s_at

203142_PM_s_at

203142_s_at

2863748

2863749

2863750

2863751

2863752

2863753

2863754

2863755

2863760

2863763

2863767

2863769

2863788

2863793

2863796

2863797

2863798

2863800

2863801

2863802

2863804

2863805

2863807

2863808

2863809

2863810

2863813

2863814

2863815

2863817

2863818

2863819

2863821

2863822

2863823

2863825

2863827

2863832

2863833

2863834

32039_at

8112772

8546

89136_at

A_23_P136635

A_32_P47510

GE81313

GE861854

GO:0000902

GO:0002224

GO:0002244

GO:0002376

GO:0003016

GO:0005515

GO:0005739

GO:0005764

GO:0005765

GO:0005768

GO:0005769

GO:0005773

GO:0005794

GO:0006351

GO:0006355

GO:0006622

GO:0006882

GO:0006886

GO:0006954

GO:0007005

GO:0007018

GO:0007040

GO:0007155

GO:0007283

GO:0007338

GO:0007596

GO:0008089

GO:0015031

GO:0016020

GO:0016071

GO:0016192

GO:0019882

GO:0019903

GO:0022414

GO:0023052

GO:0030117

GO:0030123

GO:0030131

GO:0030154

GO:0030324

GO:0030665

GO:0030742

GO:0030851

GO:0031410

GO:0032438

GO:0034394

GO:0035654

GO:0036211

GO:0042060

GO:0042789

GO:0043226

GO:0043473

GO:0045944

GO:0046907

GO:0048007

GO:0048490

GO:0048856

GO:0048872

GO:0050790

GO:0051138

GO:0055065

GO:0060155

GO:0060425

GO:0061024

GO:0090152

GO:0098773

GO:1903232

GO:1904115

HMNXSV003012130

HMNXSV003041496

HMNXSV003049107

Hs.155172.0.S1_3p_a_at

ILMN_1768867

PH_hs_0012882

PH_hs_0026120

TC05001513.hg

U91931_at

g4501974_3p_a_at

Participates

as a candidate of

Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)

Other forms of this molecule

AP3B1 [cytoplasmic vesicle membrane]

AP3B1(1-859)-BRAF(381-766) fusion [cytosol]

AP3B1(1-859)-p-BRAF(381-766) fusion [cytosol]

Inferred To

ap3b-2 [Golgi membrane] (Dictyostelium discoideum)

ap3b1 [Golgi membrane] (Xenopus tropicalis)

APL6 [Golgi membrane] (Saccharomyces cerevisiae)

apb-3 [Golgi membrane] (Caenorhabditis elegans)

Ap3b1 [Golgi membrane] (Mus musculus)

rb [Golgi membrane] (Drosophila melanogaster)

AP3B1 [Golgi membrane] (Bos taurus)

AP3B1 [Golgi membrane] (Canis familiaris)

AP3B1 [Golgi membrane] (Gallus gallus)

AP3B1 [Golgi membrane] (Plasmodium falciparum)

AP3B1 [Golgi membrane] (Rattus norvegicus)

AP3B1 [Golgi membrane] (Sus scrofa)

Cross References

RefSeq

NP_001258698.1, NP_003655.3

OpenTargets

ENSG00000132842

GeneCards

O00203

HPA

ENSG00000132842-AP3B1

Ensembl

ENST00000519295, ENSG00000132842, ENST00000255194, ENSP00000430597, ENSP00000255194

PRO

O00203

Pharos - Targets

O00203

Orphanet

15934

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.564	2
UniProt:Q96CV9 OPTN	5	OPTN [recycling endosome membrane] (R-HSA-8854141) p-S177-OPTN [nucleoplasm] (R-HSA-2562595) p-S177-OPTN [cytosol] (R-HSA-2562525) OPTN [Golgi membrane] (R-HSA-2161111) OPTN [cytosol] (R-HSA-9687907)	0.556	3
UniProt:P37840 SNCA	5	SNCA A30P [cytosol] (R-HSA-5658569) SNCA [extracellular region] (R-HSA-976954) Ub-SNCA [cytosol] (R-HSA-5660754) p-S129-SNCA [cytosol] (R-HSA-9836432) SNCA [cytosol] (R-HSA-5658500)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	6
UniProt:P0DTC4 E	9	N-glycan E [endoplasmic reticulum lumen] (R-COV-9694754) nascent E [endoplasmic reticulum lumen] (R-COV-9694312) 3xPalmC-E [endoplasmic reticulum lumen] (R-COV-9694305) Ub-3xPalmC-E [endoplasmic reticulum lumen] (R-COV-9694423) Ub-3xPalmC-E [endoplasmic reticulum membrane] (R-COV-9694465) Ub-3xPalmC-E [Golgi membrane] (R-COV-9694687) Ub-3xPalmC-E [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698420) Ub-3xPalmC-E [endocytic vesicle membrane] (R-COV-9698422) Ub-3xPalmC-E [virion membrane] (R-COV-9698416)	0.527	2