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NECAP1 [Golgi membrane]
Stable Identifier
R-HSA-434327
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
Adaptin ear-binding coat-associated protein 1, NECP1_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Golgi Associated Vesicle Biogenesis (Homo sapiens)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
NECAP1 [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
NECAP1 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Coat Assembly (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
NECAP1 [Golgi membrane] (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
NECAP1 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Vesicle Scission (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
NECAP1 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8NC96 NECAP1
Gene Names
NECAP1
Chain
chain:1-275
Reference Genes
BioGPS Gene:25977 NECAP1
COSMIC (genes):NECAP1 NECAP1
CTD Gene:25977 NECAP1
dbSNP Gene:25977 NECAP1
ENSEMBL:ENSG00000089818 NECAP1
ENSEMBL_homo_sapiens_GENE:ENSG00000089818.18 NECAP1
HGNC:24539 NECAP1
KEGG Gene (Homo sapiens):25977 NECAP1
Monarch:25977 NECAP1
NCBI Gene:25977 NECAP1
OMIM:611623 NECAP1
UCSC:Q8NC96 NECAP1
Reference Transcript
RefSeq:NM_015509.3 NECAP1
Other Identifiers
11717572_a_at
11717573_s_at
11747668_a_at
11751439_a_at
16747835
209300_PM_s_at
209300_s_at
25977
3046418
3403571
3403572
3403574
3403576
3403578
3403580
3403581
3403583
3403584
3403586
3403587
3403588
3403589
3403590
3403591
3796374
41662_at
7953715
A_24_P116132
GE56283
GO:0005515
GO:0005829
GO:0005886
GO:0005905
GO:0006897
GO:0015031
GO:0016020
GO:0016192
GO:0030125
GO:0030665
GO:0031410
GO:0043226
HMNXSV003033084
ILMN_1726359
PH_hs_0025721
TC12000113.hg
TC12002216.hg
g12804070_3p_a_at
Participates
as a candidate of
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
Other forms of this molecule
NECAP1 [cytosol]
NECAP1 [cytoplasmic vesicle membrane]
Inferred To
ncap-1 [Golgi membrane]
(Caenorhabditis elegans)
NECAP1 [Golgi membrane]
(Bos taurus)
NECAP1 [Golgi membrane]
(Canis familiaris)
NECAP1 [Golgi membrane]
(Dictyostelium discoideum)
NECAP1 [Golgi membrane]
(Drosophila melanogaster)
NECAP1 [Golgi membrane]
(Gallus gallus)
NECAP1 [Golgi membrane]
(Sus scrofa)
necap1 [Golgi membrane]
(Xenopus tropicalis)
Necap1 [Golgi membrane]
(Mus musculus)
Necap1 [Golgi membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_056324.2
OpenTargets
ENSG00000089818
GeneCards
Q8NC96
HPA
ENSG00000089818-NECAP1
Ensembl
ENST00000450991
,
ENSP00000401963
,
ENSP00000341737
,
ENST00000339754
,
ENSG00000089818
,
ENSP00000491067
,
ENST00000639955
PRO
Q8NC96
Pharos - Targets
Q8NC96
Orphanet
22814
PDB
6RH5
,
6RH6
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96CW1 AP2M1
6
AP2M1 [plasma membrane]
(R-HSA-167585)
AP2M1 [lysosomal membrane]
(R-HSA-196144)
AP2M1 [cytosol]
(R-HSA-182227)
AP2M1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130423)
AP2M1 [endolysosome membrane]
(R-HSA-6784828)
p-T156 AP2M1 [cytosol]
(R-HSA-8856805)
0.643
3
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