Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
BLOC1S1 [Golgi membrane]
Stable Identifier
R-HSA-434324
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
Biogenesis of lysosome-related organelles complex 1 subunit 1, BL1S1_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Lysosome Vesicle Biogenesis (Homo sapiens)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane (Homo sapiens)
Lysosome Destined Cargo [Golgi membrane] (Homo sapiens)
BLOC1S1 [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo [Golgi membrane] (Homo sapiens)
BLOC1S1 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Lysosomal Vesicle Scission (Homo sapiens)
Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo [Golgi membrane] (Homo sapiens)
BLOC1S1 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Homo sapiens)
Lysosome Destined Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo [Golgi membrane] (Homo sapiens)
BLOC1S1 [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo [Golgi membrane] (Homo sapiens)
BLOC1S1 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P78537 BLOC1S1
Gene Names
BLOC1S1, BLOS1, GCN5L1, RT14
Chain
chain:1-153
Reference Genes
BioGPS Gene:2647 BLOC1S1
COSMIC (genes):BLOC1S1 BLOC1S1
CTD Gene:2647 BLOC1S1
dbSNP Gene:2647 BLOC1S1
ENSEMBL:ENSG00000135441 BLOC1S1
HGNC:4200 BLOC1S1
KEGG:hsa:2647 BLOC1S1
Monarch:2647 BLOC1S1
NCBI Gene:2647 BLOC1S1
OMIM:601444 BLOC1S1
UCSC:P78537 BLOC1S1
Reference Transcript
RefSeq:NM_001487.4 BLOC1S1
Other Identifiers
11716289_a_at
202592_PM_at
202592_at
236291_PM_at
236291_at
2647
3416910
3416911
3416912
3416914
3416915
3416917
3416918
3416919
3416920
3416922
3416923
39133_at
7956013
87407_at
A_23_P53298
A_33_P3388870
GE57286
GO:0003824
GO:0005515
GO:0005615
GO:0005737
GO:0005739
GO:0005758
GO:0005759
GO:0005764
GO:0005765
GO:0005768
GO:0005769
GO:0005773
GO:0005829
GO:0006091
GO:0007018
GO:0008089
GO:0009060
GO:0016020
GO:0016192
GO:0016197
GO:0016740
GO:0018394
GO:0031083
GO:0031175
GO:0031410
GO:0032418
GO:0032438
GO:0043226
GO:0048490
GO:0051036
GO:0060155
GO:0061733
GO:0062196
GO:0072384
GO:0098574
GO:0099078
GO:0140096
GO:1904115
HMNXSV003032443
HMNXSV003032470
Hs.222853.0.S1_3p_at
ILMN_2157510
PH_hs_0005179
S82447_s_at
TC12002384.hg
TC12003299.hg
g4503954_3p_at
p24922
Participates
as a candidate of
Lysosome Destined Cargo [Golgi membrane] (Homo sapiens)
Other forms of this molecule
BLOC1S1 [lysosomal membrane]
Inferred To
blos-1 [Golgi membrane]
(Caenorhabditis elegans)
BLOC1S1 [Golgi membrane]
(Bos taurus)
BLOC1S1 [Golgi membrane]
(Canis familiaris)
BLOC1S1 [Golgi membrane]
(Gallus gallus)
BLOC1S1 [Golgi membrane]
(Sus scrofa)
Blos1 [Golgi membrane]
(Drosophila melanogaster)
Bloc1s1 [Golgi membrane]
(Mus musculus)
Bloc1s1 [Golgi membrane]
(Rattus norvegicus)
bloc1s1 [Golgi membrane]
(Danio rerio)
bloc1s1 [Golgi membrane]
(Dictyostelium discoideum)
bloc1s1 [Golgi membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001478.2
ENSEMBL
ENST00000548925
,
ENSP00000447537
,
ENSG00000135441
OpenTargets
ENSG00000135441
GeneCards
BLOC1S1
HPA
ENSG00000135441-BLOC1S1
PRO
P78537
Pharos - Targets
P78537
Interactors (16)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UL45 BLOC1S6
1
BLOC1S6 [cytosol]
(R-HSA-429816)
0.887
20
UniProt:O95295 SNAPIN
2
SNAPIN [Golgi membrane]
(R-HSA-434344)
SNAPIN [cytoplasmic vesicle membrane]
(R-HSA-434204)
0.814
8
UniProt:Q96EV8 DTNBP1
1
DTNBP1 [cytosol]
(R-HSA-429819)
0.764
6
UniProt:Q6QNY1 BL1S2
0.701
5
UniProt:Q9NUP1 BLOC1S4
1
BLOC1S4 [cytosol]
(R-HSA-429817)
0.664
5
UniProt:Q8TDH9 BL1S5
0.648
4
UniProt:Q6QNY0 BLOC1S3
1
BLOC1S3 [cytosol]
(R-HSA-429820)
0.648
4
UniProt:Q8N6Y0 USBP1
0.556
3
UniProt:O75971-2 SNAPC5
0.556
3
UniProt:O15481 MAGB4
0.556
3
UniProt:Q9H4M3-2 FBXO44
0.556
3
UniProt:O14964 HGS
2
HGS [cytosol]
(R-HSA-182954)
HGS [phagocytic vesicle lumen]
(R-HSA-9635660)
0.556
3
UniProt:Q13561 DCTN2
1
DCTN2 [cytosol]
(R-HSA-380302)
0.556
3
UniProt:Q96FH0 BORC8
0.527
3
UniProt:Q9BQD3 KXDL1
0.527
3
UniProt:Q16795 NDUFA9
1
NDUFA9 [mitochondrial matrix]
(R-HSA-163942)
0.524
3
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text