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DNASE2 [Golgi lumen]
Stable Identifier
R-HSA-434322
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
Deoxyribonuclease-2-alpha, DNS2A_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Lysosome Vesicle Biogenesis (Homo sapiens)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane (Homo sapiens)
Lysosome Destined Cargo [Golgi lumen] (Homo sapiens)
DNASE2 [Golgi lumen] (Homo sapiens)
Lysosome Destined Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo [Golgi lumen] (Homo sapiens)
DNASE2 [Golgi lumen] (Homo sapiens)
trans-Golgi Network Lysosomal Vesicle Scission (Homo sapiens)
Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo [Golgi lumen] (Homo sapiens)
DNASE2 [Golgi lumen] (Homo sapiens)
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Homo sapiens)
Lysosome Destined Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo [Golgi lumen] (Homo sapiens)
DNASE2 [Golgi lumen] (Homo sapiens)
Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo [Golgi lumen] (Homo sapiens)
DNASE2 [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00115 DNASE2
Gene Names
DNASE2, DNASE2A, DNL2
Chain
signal peptide:1-18, chain:19-360
Reference Genes
BioGPS Gene:1777 DNASE2
COSMIC (genes):DNASE2 DNASE2
CTD Gene:1777 DNASE2
dbSNP Gene:1777 DNASE2
ENSEMBL:ENSG00000105612 DNASE2
HGNC:2960 DNASE2
KEGG Gene (Homo sapiens):1777 DNASE2
Monarch:1777 DNASE2
NCBI Gene:1777 DNASE2
OMIM:126350 DNASE2
UCSC:O00115 DNASE2
Reference Transcript
RefSeq:NM_001375.2 DNASE2
Other Identifiers
0004810059
11730732_at
11730733_x_at
11749450_a_at
16869350
1747_at
1777
209831_x_at
214992_s_at
3851825
3851827
3851828
3851829
3851830
3851831
3851832
3851833
3851834
3851836
3851837
3851838
3851839
8034565
AD000092_cds2_at
A_23_P119266
GE54554
GO:0000737
GO:0002376
GO:0003674
GO:0003677
GO:0004518
GO:0004519
GO:0004520
GO:0004531
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005764
GO:0005773
GO:0006259
GO:0006308
GO:0006309
GO:0006915
GO:0007275
GO:0008150
GO:0008219
GO:0009056
GO:0016787
GO:0030154
GO:0030218
GO:0034641
GO:0034655
GO:0042592
GO:0043226
GO:0048856
GO:0050776
GO:0070062
HMNXSV003034372
Hs.307251.0.S1_3p_s_at
ILMN_1796245
PH_hs_0006502
TC19001212.hg
g3184394_3p_at
g3184394_3p_x_at
Participates
as a candidate of
Lysosome Destined Cargo [Golgi lumen] (Homo sapiens)
Other forms of this molecule
DNASE2 [lysosomal lumen]
Inferred To
dnase2 [Golgi lumen]
(Danio rerio)
DNaseII [Golgi lumen]
(Drosophila melanogaster)
DNASE2 [Golgi lumen]
(Canis familiaris)
DNASE2 [Golgi lumen]
(Dictyostelium discoideum)
DNASE2 [Golgi lumen]
(Sus scrofa)
Dnase2 [Golgi lumen]
(Mus musculus)
Dnase2 [Golgi lumen]
(Rattus norvegicus)
crn-7 [Golgi lumen]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001366.1
OpenTargets
ENSG00000105612
GeneCards
O00115
HPA
ENSG00000105612-DNASE2
Ensembl
ENST00000222219
,
ENSP00000222219
,
ENSG00000105612
ZINC target
O00115
PRO
O00115
Pharos - Targets
O00115
GlyGen
O00115
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