Cis-homodimerization of nectins

Stable Identifier
R-HSA-433711
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Cis-homodimerization of nectins
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The Nectin family of Ca2+-independent cell adhesion molecules (CAMs) is comprised of four members, nectin-1, nectin-2, nectin-3, and nectin-4 (reviewed in Sakisaka et al., 2007). Each nectin first forms homophilic cis-dimers and then forms homophilic or heterophilic trans-dimers involved in cell–cell adhesion. Heterophilic trans-interactions are stronger than homophilic trans-interactions.
Literature References
PubMed ID Title Journal Year
9845526 The human poliovirus receptor related 2 protein is a new hematopoietic/endothelial homophilic adhesion molecule

Gomez, S, Dubreuil, P, Isnardon, D, Aoubala, M, Lopez, M, Jordier, F

Blood 1998
Participants
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Output
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Orthologous Events
Cis-homodimerization of nectins (Bos taurus)
Cis-homodimerization of nectins (Caenorhabditis elegans)
Cis-homodimerization of nectins (Canis familiaris)
Cis-homodimerization of nectins (Danio rerio)
Cis-homodimerization of nectins (Drosophila melanogaster)
Cis-homodimerization of nectins (Gallus gallus)
Cis-homodimerization of nectins (Mus musculus)
Cis-homodimerization of nectins (Rattus norvegicus)
Cis-homodimerization of nectins (Sus scrofa)
Cis-homodimerization of nectins (Xenopus tropicalis)
Authored
Matthews, L  (2009-08-19)
Reviewed
Ebnet, K  (2009-08-27)
Created
Matthews, L  (2009-08-25)
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