Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
User Guide
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Author/Reviewer Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
User Guide
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Author/Reviewer Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Download
Search ...
Go!
TGFBR2:CBL
Stable Identifier
R-HSA-4332229
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by TGF-beta family members (Homo sapiens)
Signaling by TGF-beta Receptor Complex (Homo sapiens)
TGF-beta receptor signaling activates SMADs (Homo sapiens)
CBL binds TGFBR2 (Homo sapiens)
TGFBR2:CBL [plasma membrane] (Homo sapiens)
CBL neddylates TGFBR2 (Homo sapiens)
TGFBR2:CBL [plasma membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
23290524
c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-? type II receptor
Mol. Cell
2013
Participants
components
CBL [cytosol] (Homo sapiens)
TGFBR2 [plasma membrane] (Homo sapiens)
Participant Of
input
CBL neddylates TGFBR2
output
CBL binds TGFBR2
Inferred To
TGFBR2:CBL [plasma membrane] (Bos taurus)
TGFBR2:CBL [plasma membrane] (Canis familiaris)
TGFBR2:CBL [plasma membrane] (Danio rerio)
TGFBR2:CBL [plasma membrane] (Gallus gallus)
TGFBR2:CBL [plasma membrane] (Mus musculus)
TGFBR2:CBL [plasma membrane] (Rattus norvegicus)
TGFBR2:CBL [plasma membrane] (Sus scrofa)
TGFBR2:CBL [plasma membrane] (Taeniopygia guttata)
TGFBR2:CBL [plasma membrane] (Xenopus tropicalis)
© 2018
Reactome
