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SLC10A6 [plasma membrane]
Stable Identifier
R-HSA-433091
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
SOAT, Solute carrier family 10 member 6, SOAT_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q53HI1 UNC50
Expand all
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
SOAT can transport taurolithocholate-3-sulphate (Homo sapiens)
SLC10A6 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q3KNW5 SLC10A6
Gene Names
SLC10A6, SOAT
Chain
chain:1-377
Reference Genes
BioGPS Gene:345274 SLC10A6
COSMIC (genes):SLC10A6 SLC10A6
CTD Gene:345274 SLC10A6
dbSNP Gene:345274 SLC10A6
ENSEMBL:ENSG00000145283 SLC10A6
ENSEMBL_homo_sapiens_GENE:ENSG00000145283.8 SLC10A6
HGNC:30603 SLC10A6
KEGG Gene (Homo sapiens):345274 SLC10A6
Monarch:345274 SLC10A6
NCBI Gene:345274 SLC10A6
OMIM:613366 SLC10A6
UCSC:Q3KNW5 SLC10A6
Reference Transcript
RefSeq:NM_197965.2 SLC10A6
Other Identifiers
11738425_at
16977760
2776839
2776840
2776841
2776842
2776843
2776844
2776846
2776847
2776848
345274
8101609
A_33_P3212102
GE489993
GO:0005215
GO:0005515
GO:0005886
GO:0006811
GO:0006814
GO:0006869
GO:0008508
GO:0015293
GO:0015721
GO:0016020
GO:0043250
GO:0043251
GO:0055085
HMNXSV003037610
ILMN_1792933
PH_hs_0030422
TC04001359.hg
Inferred To
slc10a6 [plasma membrane]
(Xenopus tropicalis)
Dmel\CG11655 [plasma membrane]
(Drosophila melanogaster)
SLC10A6 [plasma membrane]
(Bos taurus)
SLC10A6 [plasma membrane]
(Caenorhabditis elegans)
SLC10A6 [plasma membrane]
(Canis familiaris)
SLC10A6 [plasma membrane]
(Sus scrofa)
Slc10a6 [plasma membrane]
(Mus musculus)
Slc10a6 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_932069.1
Guide to Pharmacology - Targets
961
OpenTargets
ENSG00000145283
GeneCards
Q3KNW5
HPA
ENSG00000145283-SLC10A6
Ensembl
ENSP00000273905
,
ENSG00000145283
,
ENST00000273905
PRO
Q3KNW5
Pharos - Targets
Q3KNW5
HMDB Protein
HMDBP09095
Interactors (146)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15041 AR6P1
0.556
3
UniProt:Q9NZ01 TECR
1
TECR [endoplasmic reticulum membrane]
(R-HSA-548663)
0.556
3
UniProt:Q6ZPD8 DGAT2L6
1
DGAT2L6 [endoplasmic reticulum membrane]
(R-HSA-8848588)
0.556
3
UniProt:Q5RI15 COX20
1
COX20 [mitochondrial inner membrane]
(R-HSA-5336169)
0.556
3
UniProt:O60636 TSN2
0.556
3
UniProt:Q13021 MALL
0.556
3
UniProt:Q92520 FAM3C
2
FAM3C [extracellular region]
(R-HSA-8848922)
FAM3C [platelet dense granule lumen]
(R-HSA-8848884)
0.556
3
UniProt:Q9H2L4 TMM60
0.556
3
UniProt:Q96MV8 ZDH15
0.556
3
UniProt:B2RUZ4 SMIM1
0.556
3
UniProt:P78329 CYP4F2
1
CYP4F2 [endoplasmic reticulum membrane]
(R-HSA-211016)
0.556
3
UniProt:A2RU14 TM218
0.556
3
UniProt:Q86Y82 STX12
0.556
3
UniProt:P57105 SYJ2B
0.556
3
UniProt:O14735 CDIPT
1
CDIPT [endoplasmic reticulum membrane]
(R-HSA-1498749)
0.556
3
UniProt:Q9H0Q3 FXYD6
1
FXYD6 [plasma membrane]
(R-HSA-2752104)
0.556
3
UniProt:Q99726 SLC30A3
1
SLC30A3 [synaptic vesicle membrane]
(R-HSA-437087)
0.556
3
UniProt:Q8N661 TMEM86B
1
TMEM86B [endoplasmic reticulum membrane]
(R-HSA-8874443)
0.556
3
UniProt:Q6N075 MFSD5
0.556
3
UniProt:P02808 STAT
0.556
3
UniProt:O95452 GJB6
1
GJB6 [endoplasmic reticulum membrane]
(R-HSA-190633)
0.556
3
UniProt:Q9Y3D6 FIS1
2
FIS1 [peroxisomal membrane]
(R-HSA-9033123)
FIS1 [cytosol]
(R-HSA-9033099)
0.556
3
UniProt:Q0VAQ4 SMAGP
0.556
3
UniProt:Q96F05 CK024
0.556
3
UniProt:Q96AG3 S2546
0.556
3
UniProt:Q9H9B4 SFXN1
0.556
3
UniProt:Q9NUM3 S39A9
0.556
3
UniProt:Q8IXM6 NRM
0.556
3
UniProt:Q7Z6L0 PRRT2
0.556
3
UniProt:O95562 SFT2B
0.556
3
UniProt:Q99650 OSMR
1
OSMR [plasma membrane]
(R-HSA-448654)
0.556
3
UniProt:P05090 APOD
1
APOD [extracellular region]
(R-HSA-5216199)
0.556
3
UniProt:Q9Y6G1 TM14A
0.556
3
UniProt:Q13433-2 SLC39A6
0.556
3
UniProt:Q86T03 TMEM55B
2
TMEM55B [late endosome membrane]
(R-HSA-6810395)
TMEM55B [nucleoplasm]
(R-HSA-6810405)
0.556
3
UniProt:Q8N6L7 TM252
0.556
3
UniProt:O15400 STX7
0.556
3
UniProt:Q6UX40 TM107
0.556
3
UniProt:A0AVG3 A0AVG3
0.556
3
UniProt:Q9Y548 YIPF1
0.556
3
UniProt:Q969E2 SCAM4
0.556
3
UniProt:Q8TDV0 GP151
0.556
3
UniProt:Q8IVJ1 SLC41A1
1
SLC41A1 [plasma membrane]
(R-HSA-442659)
0.556
3
UniProt:I3L0A0 I3L0A0
0.556
3
UniProt:Q9Y385 UBE2J1
1
UBE2J1 [cytosol]
(R-HSA-947625)
0.556
3
UniProt:Q92903 CDS1
1
CDS1 [endoplasmic reticulum membrane]
(R-HSA-1498762)
0.556
3
UniProt:P29400-2 COL4A5
0.556
3
UniProt:O43759-2 SYNGR1
0.556
3
UniProt:O95393 BMP10
2
BMP10(22-424) [extracellular region]
(R-HSA-2396409)
BMP10 [extracellular region]
(R-HSA-8858374)
0.556
3
UniProt:Q9BTX3 TM208
0.556
3
UniProt:P48230 T4S4
0.556
3
UniProt:Q96GQ5 RUSF1
0.556
3
UniProt:E9PQX1 TM262
0.556
3
UniProt:O95159 ZFPL1
0.556
3
UniProt:P02787 TF
6
apoTF [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869140)
TF [secretory granule lumen]
(R-HSA-350704)
apoTF [extracellular region]
(R-HSA-350754)
apoTF [endosome membrane]
(R-HSA-917974)
p-TF [endoplasmic reticulum lumen]
(R-HSA-8957001)
TF [endoplasmic reticulum lumen]
(R-HSA-8956763)
0.556
3
UniProt:Q96AN5 TM143
0.556
3
UniProt:Q9UNK0 STX8
0.556
3
UniProt:Q96IV6 FXDC2
0.556
3
UniProt:Q5BJH2-2 TMEM128
0.556
3
UniProt:Q6ZSS7 MFSD6
0.556
3
UniProt:P21964 COMT
2
COMT [plasma membrane]
(R-HSA-379386)
COMT [cytosol]
(R-HSA-175974)
0.556
3
UniProt:Q8NBD8 T229B
0.556
3
UniProt:Q8N2U9 S66A2
0.556
3
UniProt:Q8N2M4 TM86A
0.556
3
UniProt:Q6UX34 SNORC
0.556
3
UniProt:Q9Y6X1 SERP1
2
SERP1 [endoplasmic reticulum membrane]
(R-HSA-381045)
SERP1 [cytosol]
(R-HSA-5250574)
0.556
3
UniProt:Q86W74-2 ANKRD46
0.556
3
UniProt:Q9NZG7 NINJ2
0.556
3
UniProt:A0A0C4DFN3 A0A0C4DFN3
0.556
3
UniProt:Q99519 NEU1
8
NEU1 W23* [lysosomal lumen]
(R-HSA-5674155)
NEU1 W29* [lysosomal lumen]
(R-HSA-5674174)
NEU1 E377* [lysosomal lumen]
(R-HSA-5674181)
NEU1 R225P [lysosomal lumen]
(R-HSA-5674167)
NEU1 L303P [lysosomal lumen]
(R-HSA-5674182)
NEU1 [extracellular region]
(R-HSA-6806158)
NEU1 [specific granule lumen]
(R-HSA-6806148)
NEU1 [lysosomal lumen]
(R-HSA-1605788)
0.556
3
UniProt:O60831 PRAF2
0.556
3
UniProt:Q14802-3 FXYD3
0.556
3
UniProt:Q9BV81 EMC6
0.556
3
UniProt:P11836 CD20
0.556
3
UniProt:Q9Y225-2 RNF24
0.556
3
UniProt:Q6PI78 TMM65
0.556
3
UniProt:Q9Y666-2 SLC12A7
0.556
3
UniProt:Q9NZ42 PSENEN
2
PSENEN [endosome membrane]
(R-HSA-9010101)
PSENEN [plasma membrane]
(R-HSA-157331)
0.556
3
UniProt:O75379 VAMP4
4
VAMP4 [transport vesicle]
(R-HSA-6811023)
VAMP4 [trans-Golgi network membrane]
(R-HSA-6811021)
VAMP4 [plasma membrane]
(R-HSA-8864461)
VAMP4 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869133)
0.556
3
UniProt:Q9UBY5 LPAR3
1
LPAR3 [plasma membrane]
(R-HSA-419379)
0.556
3
UniProt:Q8WW34-2 TMEM239
0.556
3
UniProt:O14653 GOSR2
4
GOSR2 [endoplasmic reticulum membrane]
(R-HSA-5689451)
GOSR2 [ER to Golgi transport vesicle membrane]
(R-HSA-5689800)
GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-535472)
GOSR2 [Golgi membrane]
(R-HSA-6807755)
0.556
3
UniProt:P54315 PNLIPRP1
1
PNLIPRP1 [extracellular region]
(R-HSA-3902876)
0.556
3
UniProt:Q5TGU0 TSPO2
0.556
3
UniProt:P49768-2 PSEN1
0.556
3
UniProt:Q8N6R1 SERP2
0.556
3
UniProt:Q9BUN8 DERL1
1
DERL1 [endoplasmic reticulum membrane]
(R-HSA-6781898)
0.556
3
UniProt:Q969S6 TM203
0.556
3
UniProt:Q9UKR5 ERG28
0.556
3
UniProt:Q8WWP7 GIMA1
0.556
3
UniProt:Q96DZ9-2 CMTM5
0.556
3
UniProt:Q96EC8 YIPF6
2
YIPF6 [Golgi membrane]
(R-HSA-434346)
YIPF6 [cytoplasmic vesicle membrane]
(R-HSA-434199)
0.556
3
UniProt:Q9NTJ5 SACM1L
2
SACM1L [endoplasmic reticulum membrane]
(R-HSA-1604637)
SACM1L [Golgi membrane]
(R-HSA-1806242)
0.556
3
UniProt:Q9NWH2 TM242
0.556
3
UniProt:P16278 GLB1
8
GLB1 W509C [lysosomal lumen]
(R-HSA-2262732)
GLB1 Y83C [lysosomal lumen]
(R-HSA-2262735)
GLB1 R482C [lysosomal lumen]
(R-HSA-2262739)
GLB1 W273L [lysosomal lumen]
(R-HSA-2262738)
GLB1 [ficolin-1-rich granule lumen]
(R-HSA-6800968)
GLB1 [lysosomal lumen]
(R-HSA-1605623)
GLB1 [azurophil granule lumen]
(R-HSA-6799124)
GLB1 [extracellular region]
(R-HSA-6806213)
0.556
3
UniProt:Q14318 FKBP8
2
PolyUb-FKBP8 [mitochondrial outer membrane]
(R-HSA-6783001)
FKBP8 [mitochondrial outer membrane]
(R-HSA-5696928)
0.556
3
UniProt:Q9H2H9 SLC38A1
1
SLC38A1 [plasma membrane]
(R-HSA-212663)
0.556
3
UniProt:P00387 CYB5R3
3
MyrG-CYB5R3(2-301) [mitochondrial outer membrane]
(R-HSA-198771)
CYB5R3(27-301) [extracellular region]
(R-HSA-6806205)
CYB5R3(27-301) [azurophil granule lumen]
(R-HSA-6799217)
0.556
3
UniProt:Q9UHE5 NAT8
1
NAT8 [endoplasmic reticulum membrane]
(R-HSA-5692986)
0.556
3
UniProt:O14523 C2C2L
0.556
3
UniProt:Q6ZUI0 TPRG1
0.556
3
UniProt:P48449 LSS
1
LSS [endoplasmic reticulum membrane]
(R-HSA-191371)
0.556
3
UniProt:P02724 GYPA
1
GYPA [plasma membrane]
(R-HSA-8867204)
0.556
3
UniProt:Q8TAC9 SCAM5
0.556
3
UniProt:A0PK00 T120B
0.556
3
UniProt:P13236 CCL4
1
CCL4(24-92) [extracellular region]
(R-HSA-443976)
0.556
3
UniProt:Q8WY98 TM234
0.556
3
UniProt:Q9BUP3-3 HTATIP2
0.556
3
UniProt:Q96FB2 Q96FB2
0.556
3
UniProt:Q8TBE7 S35G2
0.556
3
UniProt:Q03518 TAP1
3
TAP1 [phagocytic vesicle membrane]
(R-HSA-1236845)
TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-8863953)
TAP1 [endoplasmic reticulum membrane]
(R-HSA-947474)
0.556
3
UniProt:Q9P0B6 CC167
0.556
3
UniProt:Q9HD20-3 ATP13A1
0.556
3
UniProt:P60201-2 PLP1
0.556
3
UniProt:Q8NHS1 CLDN2
0.556
3
UniProt:Q9Y3E0 GOT1B
0.556
3
UniProt:P11215 ITGAM
3
ITGAM [specific granule membrane]
(R-HSA-6799647)
ITGAM [tertiary granule membrane]
(R-HSA-6800979)
ITGAM [plasma membrane]
(R-HSA-202757)
0.556
3
UniProt:O95406 CNIH1
3
CNIH1 [endoplasmic reticulum membrane]
(R-HSA-5689439)
CNIH1 [ER to Golgi transport vesicle membrane]
(R-HSA-5689776)
CNIH1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5689778)
0.556
3
UniProt:P56557 TM50B
0.556
3
UniProt:Q53HI1 UNC50
0.556
3
UniProt:Q9BWH2 FUND2
0.556
3
UniProt:Q9Y5Y5 PEX16
2
PEX16 [peroxisomal membrane]
(R-HSA-9603805)
PEX16 [cytosol]
(R-HSA-9603790)
0.556
3
UniProt:Q9NQQ7-3 Q9NQQ73
0.556
3
UniProt:Q8N4L2 PP4P2
0.556
3
UniProt:Q9Y342 PLLP
0.556
3
UniProt:Q9BRI3 SLC30A2
2
SLC30A2 [endosome membrane]
(R-HSA-435363)
SLC30A2 [synaptic vesicle membrane]
(R-HSA-4084714)
0.556
3
UniProt:Q8WVV5 BTN2A2
1
BTN2A2 [plasma membrane]
(R-HSA-8851047)
0.556
3
UniProt:P24593 IGFBP5
5
IGFBP5 [endoplasmic reticulum lumen]
(R-HSA-8956738)
p-IGFBP5 [endoplasmic reticulum lumen]
(R-HSA-8956988)
IGFBP5 [extracellular region]
(R-HSA-381414)
IGFBP5(21-163) [extracellular region]
(R-HSA-381415)
IGFBP5(164-272) [extracellular region]
(R-HSA-381478)
0.556
3
UniProt:Q5QGT7 RTP2
2
RTP2 [endoplasmic reticulum membrane]
(R-HSA-9752982)
RTP2 [plasma membrane]
(R-HSA-8939446)
0.556
3
UniProt:Q9H2C2 ARV1
1
ARV1 [endoplasmic reticulum membrane]
(R-HSA-5216144)
0.556
3
UniProt:P30825 SLC7A1
1
SLC7A1 [plasma membrane]
(R-HSA-375771)
0.556
3
UniProt:P17152 TMEM11
1
TMEM11 [mitochondrial inner membrane]
(R-HSA-8949578)
0.556
3
UniProt:O00767 SCD
1
SCD [endoplasmic reticulum membrane]
(R-HSA-400117)
0.556
3
UniProt:P04921 GYPC
1
GYPC [plasma membrane]
(R-HSA-420422)
0.556
3
UniProt:Q9BWQ6 YIPF2
0.556
3
IntAct:EBI-23683896 CCSB ORF ID
0.556
3
UniProt:Q9NYZ1 TV23B
0.556
3
UniProt:Q7L5A8 FA2H
1
FA2H [endoplasmic reticulum membrane]
(R-HSA-5693771)
0.556
3
UniProt:Q9P0S3 ORMDL1
1
ORMDL1 [endoplasmic reticulum membrane]
(R-HSA-8865584)
0.556
3
UniProt:O43169 CYB5B
2
CYB5B [endoplasmic reticulum membrane]
(R-HSA-9842695)
CYB5B [mitochondrial outer membrane]
(R-HSA-8943390)
0.556
3
UniProt:Q9NSU2-1 TREX1
0.556
3
UniProt:Q01740 FMO1
1
FMO1 [endoplasmic reticulum lumen]
(R-HSA-217270)
0.556
3
UniProt:Q9ULC5 ACSL5
1
ACSL5 [endoplasmic reticulum membrane]
(R-HSA-165011)
0.556
3
IntAct:EBI-23343277 CCSB ORF ID
0.556
3
UniProt:Q8NG98 OR7D4
2
OR7D4 [endoplasmic reticulum membrane]
(R-HSA-9751364)
OR7D4 [plasma membrane]
(R-HSA-446823)
0.556
3
UniProt:Q9P0S9 TM14C
0.556
3
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